research Identification of 5α-Reductase Isoenzymes in Canine Skin
Two types of 5α-reductase are in dog skin, which might make dutasteride better than finasteride for treating dog hair loss.
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research Expression of Type 1 5α-Reductase and Metabolism of Testosterone in Reconstructed Human Epidermis: A New Model for Screening Skin-Targeted Androgen Modulators
The study created a new method to test drugs that affect hormone processing in skin.
research Persistent Erectile Dysfunction in Men Exposed to 5α-Reductase Inhibitors, Finasteride, or Dutasteride
Using finasteride or dutasteride may cause long-lasting erectile dysfunction.
research Leydig Cell Hyperplasia and Adenomas in Mice Treated with Finasteride, a 5α-Reductase Inhibitor: A Possible Mechanism
High doses of finasteride cause cell growth and tumors in mice.
research Avicequinone C Isolated from Avicennia Marina Exhibits 5α-Reductase Type 1 Inhibitory Activity Using an Androgenic Alopecia Relevant Cell-Based Assay System
Avicequinone C, a compound found in the Avicennia marina plant, can reduce hair loss by inhibiting a hormone linked to androgenic alopecia.
research Safety Aspects of Androgen Treatment with 5α-Dihydrotestosterone
DHT is a strong androgen that may pose less risk to the prostate compared to testosterone.
research Steady-State Pharmacokinetics of Oral Testosterone Undecanoate with Concomitant Inhibition of 5α-Reductase by Finasteride
Finasteride doesn't affect oral testosterone undecanoate, and high DHT levels may cause acne, prostate issues, and hair loss.
research Leydig Cell Hyperplasia and Adenomas in Mice Treated with Finasteride, a 5α-Reductase Inhibitor: A Possible Mechanism
Finasteride causes abnormal growth in male mice cells at high doses.
research Enzyme-Linked Immunosorbent Assays for Doping Control of 5α-Reductase Inhibitors Finasteride and Dutasteride
New tests detect finasteride and dutasteride in urine quickly and easily.
research Change in Prostate-Specific Antigen Concentration in Men with Prostate-Specific Antigen Less Than 2.5 ng/mL Taking Low-Dose Finasteride or Dutasteride for Male Androgenetic Alopecia
Low-dose finasteride and dutasteride reduce PSA levels by 27.8% in men with male androgenetic alopecia.
research Inhibitory Effects of Serenoa Repens on the Kinetics of Pig Prostatic Microsomal 5α-Reductase Activity
Saw palmetto extract can block the enzyme that converts testosterone in pig prostate cells.
research Effect of Pumpkin Seed Oil on Hair Growth in Men with Androgenetic Alopecia: A Randomized, Double-Blind, Placebo-Controlled Trial
Pumpkin seed oil helps hair growth in men with hair loss.
research Bacillus/Trapa Japonica Fruit Extract Ferment Filtrate Enhances Human Hair Follicle Dermal Papilla Cell Proliferation via the Akt/ERK/GSK-3β Signaling Pathway
The extract from Bacillus/Trapa japonica fruit helps increase hair growth and could be a potential treatment for hair loss.
research 5α-Reductase Inhibitors in Men Aged 50 Years or Older with Androgenetic Alopecia: A Retrospective Study
5ARI treatment improves hair growth in older men with minimal side effects.
research Trastuzumab Induced Chemobrain, Atorvastatin Rescued Chemobrain with Enhanced Anticancer Effect and without Hair Loss Side Effect
Atorvastatin reversed memory problems caused by cancer drug trastuzumab and improved its cancer-fighting abilities without causing hair loss.
research Guidelines for the Diagnosis and Treatment of Male-Pattern and Female-Pattern Hair Loss, 2017 Version
Use finasteride, dutasteride, and minoxidil for hair loss treatment.
research Hair Growth-Promotion Effects of Different Alternating Current Parameter Settings Are Mediated by the Activation of Wnt/β-Catenin and MAPK Pathway
Certain electric currents can promote hair growth by activating specific cell pathways.
research Treatment Options for Alopecia
The document concludes that oral finasteride and topical minoxidil are effective for genetic hair loss, while other treatments for different types of hair loss show promise but need more research.
research Self-Assembly of Solubilized Human Hair Keratins
Human hair keratins can form stable nanofiber networks that might help in tissue regeneration.
research Hair Regrowth
Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.
research Hair Loss in Women: Comprehensive Overview and Treatment Options
Effective hair loss treatment in women requires correct diagnosis and can include medications like minoxidil, antiandrogens, and treatments for underlying conditions like PCOS.
research Female Pattern Hair Loss
Over 50% of women over 50 experience hair loss, with minoxidil being the only proven effective treatment.
research The First Case Report of Kerion-Type Scalp Mycosis Caused by Aspergillus Protuberus
A rare fungal infection on a child's scalp was successfully treated with antifungal medication.
research Novel Progestogenic Androgens for Male Contraception: Design, Synthesis, and Activity of C7 Alpha-Substituted Testosterone
New testosterone analogs show promise for male contraception with better activity and potentially fewer side effects.
research The Effectiveness of Treatments for Androgenetic Alopecia: A Systematic Review and Meta-Analysis
Minoxidil, finasteride, and low-level laser light therapy effectively treat hair loss.
research Treatment of Frontal Fibrosing Alopecia and Lichen Planopilaris: A Systematic Review
No effective treatment for frontal fibrosing alopecia was found, but oral 5-alpha-reductase inhibitors had the best response; for lichen planopilaris, topical corticosteroids were commonly used but had a high relapse rate.
research Hair Growth and Rejuvenation: An Overview
The document concludes that minoxidil and finasteride are proven for hair growth, herbal remedies show promise, but more research is needed to confirm their effectiveness.
research Alopecia Areata: Clinical Review and Treatment Approaches
Alopecia Areata has no guaranteed treatment for hair regrowth, but options like corticosteroids and minoxidil are used, with future research focusing on genetic and immune therapies.
research Female Androgenetic Alopecia: An Update on Diagnosis and Management
FAGA diagnosis uses blood tests and trichoscopy, with treatments like topical minoxidil, oral anti-androgens, and hormone-modulating drugs.
research Medical Therapy for Frontal Fibrosing Alopecia: A Review and Clinical Approach
Some treatments like intralesional steroids and 5α-reductase inhibitors are effective for frontal fibrosing alopecia, but more research is needed.