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600-630 / 1000+ results![CRISPR/Cas9-mediated Disruption of Fibroblast Growth Factor 5 in Rabbits Results in a Systemic Long Hair Phenotype by Prolonging Anagen](/images/research/9d2312d5-d92d-478e-b2f8-5efc1ceed499/small/28993.jpg)
research CRISPR/Cas9-mediated Disruption of Fibroblast Growth Factor 5 in Rabbits Results in a Systemic Long Hair Phenotype by Prolonging Anagen
Disrupting the FGF5 gene in rabbits leads to longer hair by extending the hair growth phase.
![Effects of pre- and post-pubertal dihydrotestosterone treatment on penile length in 5α-reductase type 2 deficiency](/images/research/860437b5-e20b-4af1-a55a-7e9ca750d1c5/small/33321.jpg)
research Effects of pre- and post-pubertal dihydrotestosterone treatment on penile length in 5α-reductase type 2 deficiency
Dihydrotestosterone treatment can help penis growth in boys with 5α-reductase deficiency but doesn't fully normalize size after puberty.
research Expression of AR, 5αR1 and 5αR2 in bladder urothelial carcinoma and relationship to clinicopathological factors
Androgens may influence bladder cancer progression by affecting cellular behavior.
![Finasteride for recurrent priapism in children and adolescents: a report on 5 cases](/images/research/010740f9-b55f-46e1-9da3-8be532a1758d/small/3208.jpg)
research Finasteride for recurrent priapism in children and adolescents: a report on 5 cases
Finasteride effectively and safely treats recurrent priapism in children and adolescents with sickle cell disease.
![Erosive pustular dermatosis of the scalp from topical minoxidil 5% solution](/images/research/a98dd9df-dddc-48a0-b3b1-e2e85f8a11d4/small/26119.jpg)
research Erosive pustular dermatosis of the scalp from topical minoxidil 5% solution
A woman developed a scalp condition from using minoxidil, which improved with a different treatment but left scarring.
![Dutasteride, a novel dual 5-A reductase inhibitor, reduces serum DHT to a greater extent versus finasteride and achieves finasteride maximal reduction in a larger proportion of patients](/images/research/9d6aa470-0f1e-4f1d-9d19-39210d545277/small/2458.jpg)
research Dutasteride, a novel dual 5-A reductase inhibitor, reduces serum DHT to a greater extent versus finasteride and achieves finasteride maximal reduction in a larger proportion of patients
Dutasteride reduces DHT more effectively than finasteride.
![Impact of Alpha Blockers, 5-alpha Reductase Inhibitors and Combination Therapy on Sexual Function](/images/research/a20ec4cb-5f81-4443-bc90-54819d722a3d/small/20273.jpg)
research Impact of Alpha Blockers, 5-alpha Reductase Inhibitors and Combination Therapy on Sexual Function
Medications for enlarged prostate can cause sexual side effects like reduced libido, erectile dysfunction, and ejaculatory problems.
![Oral Testosterone With and Without Concomitant Inhibition of 5α-Reductase by Dutasteride in Hypogonadal Men for 28 Days](/images/research/4d1773f2-ea68-4048-a8d7-a729585fd733/small/14758.jpg)
research Oral Testosterone With and Without Concomitant Inhibition of 5α-Reductase by Dutasteride in Hypogonadal Men for 28 Days
Taking oral testosterone with or without dutasteride increases testosterone levels and could be an effective treatment for low testosterone.
![The Long-Term Effect Of Specific Type II 5α-Reductase Inhibition With Finasteride on Bone Mineral Density in Men: Results of a 4-Year Placebo Controlled Trial](/images/research/9e9513ca-524c-42ce-81f5-05cc4e5f6fbd/small/2404.jpg)
research The Long-Term Effect Of Specific Type II 5α-Reductase Inhibition With Finasteride on Bone Mineral Density in Men: Results of a 4-Year Placebo Controlled Trial
Finasteride doesn't harm bone density in older men with BPH.
![Sexual Problems of Men With Androgenic Alopecia Treated With 5-Alpha Reductase Inhibitors](/images/research/8d40fe60-8ad9-4f37-95e9-7f091ec29550/small/4502.jpg)
research Sexual Problems of Men With Androgenic Alopecia Treated With 5-Alpha Reductase Inhibitors
Men using hair loss drugs like finasteride may experience sexual side effects like erectile dysfunction, but it's unclear who will be affected and when. Treating depression and sexual symptoms is suggested, as these men often have higher rates of both. More research is needed to understand why these side effects occur.
![Steady-state pharmacokinetics of oral testosterone undecanoate with concomitant inhibition of 5α-reductase by finasteride](/images/research/0a7b342f-123b-421d-a334-ff5ba2feae3a/small/3100.jpg)
research Steady-state pharmacokinetics of oral testosterone undecanoate with concomitant inhibition of 5α-reductase by finasteride
Finasteride doesn't affect oral testosterone undecanoate, and high DHT levels may cause acne, prostate issues, and hair loss.
![Enzyme-linked immunosorbent assays for doping control of 5α-reductase inhibitors finasteride and dutasteride](/images/research/f298fb95-8e38-4cdf-830e-e4fa98f0a327/small/2966.jpg)
research Enzyme-linked immunosorbent assays for doping control of 5α-reductase inhibitors finasteride and dutasteride
New tests detect finasteride and dutasteride in urine quickly and easily.
![Alopecia Areata: Good Response to Treatment with Fractional Laser in 5 Cases](/images/research/ed311871-71e2-41d4-b296-843fd6c7c48a/small/16111.jpg)
research Alopecia Areata: Good Response to Treatment with Fractional Laser in 5 Cases
Fractional laser treatment helped hair regrowth in patients with alopecia areata.
![Finasteride, A Steroid 5α-Reductase Inhibitor, Does Not Affect the Oxidative Metabolism of Antipyrine](/images/research/110dc3ac-77b1-419d-95c0-d447d36ad921/small/2013.jpg)
research Finasteride, A Steroid 5α-Reductase Inhibitor, Does Not Affect the Oxidative Metabolism of Antipyrine
Finasteride doesn't affect antipyrine metabolism, so interactions with cytochrome P-450 enzyme drugs are unlikely.
research Effect of finasteride, a 5 alpha-reductase inhibitor, on serum gonadotropins in normal men
![Selective induction of apoptosis in the hamster flank sebaceous gland organ by a topical liposome 5-α-reductase inhibitor: A treatment strategy for acne](/images/research/ca170f21-a81d-4e61-b564-f26225cdad24/small/14863.jpg)
research Selective induction of apoptosis in the hamster flank sebaceous gland organ by a topical liposome 5-α-reductase inhibitor: A treatment strategy for acne
A topical treatment safely and effectively reduced acne by causing targeted cell death in sebaceous glands without side effects.
![5α-Metabolism in Finasteride-Treated Subjects and Male Pseudohermaphrodites with Inherited 5α-Reductase Deficiency](/images/research/c56815af-7198-4976-a775-df46ec2043b7/small/1955.jpg)
research 5α-Metabolism in Finasteride-Treated Subjects and Male Pseudohermaphrodites with Inherited 5α-Reductase Deficiency
Finasteride lowers DHT levels and raises testosterone in a dose-dependent way.
![Pumpkin Seed Oil-Loaded Niosomes for Topical Application: 5α-Reductase Inhibitory, Anti-Inflammatory, and In Vivo Anti-Hair Loss Effects](/images/research/aefb7092-6914-47c6-bee8-c872235eb56a/small/16897.jpg)
research Pumpkin Seed Oil-Loaded Niosomes for Topical Application: 5α-Reductase Inhibitory, Anti-Inflammatory, and In Vivo Anti-Hair Loss Effects
Pumpkin Seed Oil in niosomes may help treat hair loss and improve hair growth.
![Interconnected PolymerS TeChnology (IPSTiC): An Effective Approach for the Modulation of 5α-Reductase Activity in Hair Loss Conditions](/images/research/7a0f3f79-0be9-452c-ac96-0e3a126db07c/small/17891.jpg)
research Interconnected PolymerS TeChnology (IPSTiC): An Effective Approach for the Modulation of 5α-Reductase Activity in Hair Loss Conditions
A new anti-baldness patch effectively treats hair loss by blocking enzymes linked to the condition.
![Long-term efficacy and safety of the dual 5-alpha reductase blocker dutasteride on male androgenetic alopecia patients](/images/research/f8b37a3a-3fb6-4c61-b91f-f7ac45d372c8/small/4161.jpg)
research Long-term efficacy and safety of the dual 5-alpha reductase blocker dutasteride on male androgenetic alopecia patients
Dutasteride effectively and safely treats male hair loss for over a year.
![A homozygous missense mutation in the fibroblast growth factor 5 gene is associated with the long-hair trait in Angora rabbits](/images/research/3ae69c1c-9786-4462-8e73-db0c83285ba9/small/37042.jpg)
research A homozygous missense mutation in the fibroblast growth factor 5 gene is associated with the long-hair trait in Angora rabbits
A specific gene mutation causes long hair in Angora rabbits.
![Comparison of low-level light therapy and combination therapy of 5% minoxidil in the treatment of female pattern hair loss](/images/research/77600e16-930d-4550-bf4b-dff31c8d8698/small/5284.jpg)
research Comparison of low-level light therapy and combination therapy of 5% minoxidil in the treatment of female pattern hair loss
Combination therapy works best for female hair loss, increasing density and thickness.
![Minoxidil Acts as an Antiandrogen: A Study of 5α-reductase Type 2 Gene Expression in a Human Keratinocyte Cell Line.](/images/research/eb5b13d9-54e5-4407-ac80-29d6e3716124/small/16077.jpg)
research Minoxidil Acts as an Antiandrogen: A Study of 5α-reductase Type 2 Gene Expression in a Human Keratinocyte Cell Line.
Minoxidil may help treat hair loss by reducing the activity of a specific enzyme linked to baldness.
research Theoretical Evaluation of Twenty-Cannabinoid Derivatives on Either Androgen Receptor or 5α-Reductase Enzyme
Some cannabinoid derivatives may be more effective than current drugs at targeting proteins relevant to prostate cancer treatment.
![Pustular dermatosis of the scalp due to topical minoxidil 5%](/images/research/d1af0547-5386-45e1-b524-073a8e141652/small/11489.jpg)
research Pustular dermatosis of the scalp due to topical minoxidil 5%
A woman had an unusual allergic reaction to a hair loss treatment, which cleared up after stopping the treatment and using a different medication.
![Efficacy and safety of a novel herbal solution for the treatment of androgenetic alopecia and comparison with 5% minoxidil: A double‐blind, randomized controlled trial study](/images/research/a4f05cd7-8f3c-4145-869a-8ff5aa2276ce/small/4983.jpg)
research Efficacy and safety of a novel herbal solution for the treatment of androgenetic alopecia and comparison with 5% minoxidil: A double‐blind, randomized controlled trial study
Herbal solution improves hair diameter and density more than 5% minoxidil for androgenetic alopecia.
![Re: Risk of Erectile Dysfunction Associated with Use of 5α-Reductase Inhibitors for Benign Prostatic Hyperplasia or Alopecia: Population Based Studies Using the Clinical Practice Research Datalink](/images/research/424f2d1f-98d4-4654-b870-9592c8648a33/small/18179.jpg)
research Re: Risk of Erectile Dysfunction Associated with Use of 5α-Reductase Inhibitors for Benign Prostatic Hyperplasia or Alopecia: Population Based Studies Using the Clinical Practice Research Datalink
Using finasteride for hair loss or prostate issues does not significantly raise the risk of erectile dysfunction.
research COMPARATIVE STUDY OF EFFICACY OF PLATELET RICH PLASMA VERSUS MINOXIDIL (5%-10%) IN THE TREATMENT OF ANDROGENETIC ALOPECIA IN MALES
![46, XY 5-Alpha Reductase Deficiency in a 36-Year-Old Phenotypic Female Patient](/images/research/a9172407-4cc5-4d38-affc-fa46179cb8b8/small/32678.jpg)
research 46, XY 5-Alpha Reductase Deficiency in a 36-Year-Old Phenotypic Female Patient
A 36-year-old person with a female appearance but male chromosomes was diagnosed with a rare enzyme deficiency affecting sexual development.