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630-660 / 1000+ results![Synthesis and Study of Some 17a-aza-D-homo Steroids as 5α-Reductase Inhibitors](/images/research/8e834ee1-b252-483c-b720-01f4f66a8896/small/11558.jpg)
research Synthesis and Study of Some 17a-aza-D-homo Steroids as 5α-Reductase Inhibitors
The research found that compound 6, a newly created steroid, is more effective at inhibiting 5α-reductase (an enzyme) than current treatments, suggesting it could be a better option for treating urinary tract symptoms in men.
![Analysis of Data From Breast Diseases Treated With 5-Alpha Reductase Inhibitors for Benign Prostatic Hyperplasia](/images/research/2eb4c36c-228a-4dd0-ba26-f6a6a52e17ab/small/13511.jpg)
research Analysis of Data From Breast Diseases Treated With 5-Alpha Reductase Inhibitors for Benign Prostatic Hyperplasia
Medicines for enlarged prostate may raise the risk of breast growth and tenderness but not breast cancer.
research The Efectiveness of 0.03% Bimatoprost Solution Vs Minoxidil 5% in Androgenic Alopecia
research Efficacy and Safety of Once-Daily Minoxidil Foam 5% Versus Twice-Daily Minoxidil Solution 2% in Female Pattern Hair Loss: A Phase III, Randomized, Investigator-Blinded Study.
![Comparison of Clinical Efficacy of Finasteride and Dutasteride as 5-alpha Reductase Inhibitor](/images/research/00bd2098-6cdf-4860-ac61-fce7b4586044/small/3154.jpg)
research Comparison of Clinical Efficacy of Finasteride and Dutasteride as 5-alpha Reductase Inhibitor
Dutasteride is more effective than Finasteride in reducing prostate size and PSA levels, but both drugs have similar side effects.
![Split-scalp pilot study to evaluate effectiveness of Minoxidil 0,5% MMP® versus Topical Minoxidil 5% in the treatment of Female Pattern Hair Loss](/images/research/0e1040d3-a05a-46c0-a404-6f614b25d09a/small/37055.jpg)
research Split-scalp pilot study to evaluate effectiveness of Minoxidil 0,5% MMP® versus Topical Minoxidil 5% in the treatment of Female Pattern Hair Loss
Both treatments work, but Minoxidil 0.5% MMP® is better for certain scalp areas and less advanced hair loss.
![Phytotherapeutic Alternatives to the Use of Finasteride and Dutasteride as 5-Alpha Reductase Inhibitors in the Treatment of Androgenetic Alopecia: A Review](/images/research/c89bf98a-d28b-4f1a-9ea7-bc61123f148f/small/26952.jpg)
research Phytotherapeutic Alternatives to the Use of Finasteride and Dutasteride as 5-Alpha Reductase Inhibitors in the Treatment of Androgenetic Alopecia: A Review
Some plant-based products might treat hair loss with fewer side effects than current medications.
![Discovery of (2<i>S</i>)-<i>N</i>-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-3-(6-(4-cyanophenyl)-3,6-diazabicyclo[3.1.1]heptan-3-yl)-2-hydroxy-2-methylpropanamide as a Highly Potent and Selective Topical Androgen Receptor Antagonist for Androgenetic Alopecia Treatment](/images/research/693e7bf6-2325-4ddc-a20f-3470db9f4516/small/25627.jpg)
research Discovery of (2S)-N-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-3-(6-(4-cyanophenyl)-3,6-diazabicyclo[3.1.1]heptan-3-yl)-2-hydroxy-2-methylpropanamide as a Highly Potent and Selective Topical Androgen Receptor Antagonist for Androgenetic Alopecia Treatment
A new topical treatment for hair loss shows strong hair growth effects with low toxicity.
![mRNA Levels of Aromatase, 5α-Reductase Isozymes, and Prostate Cancer-Related Genes in Plucked Hair from Young Men with Androgenic Alopecia](/images/research/e7a87904-ba29-49d6-944d-58ba52341684/small/20553.jpg)
research mRNA Levels of Aromatase, 5α-Reductase Isozymes, and Prostate Cancer-Related Genes in Plucked Hair from Young Men with Androgenic Alopecia
Men with early balding showed higher levels of certain genes linked to hair loss and possibly prostate cancer.
![Design of Liposome Formulations for CRISPR/Cas9 Enzyme Immobilization: Evaluation of 5-Alpha-Reductase Enzyme Knockout for Androgenic Disorders](/images/research/b4b58156-99a6-405d-ac6a-f4cb11425adf/small/20558.jpg)
research Design of Liposome Formulations for CRISPR/Cas9 Enzyme Immobilization: Evaluation of 5-Alpha-Reductase Enzyme Knockout for Androgenic Disorders
New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.
![Comparative Clinical Study Evaluating the Efficacy and Safety of Topical 5% Cetosomal Minoxidil and Topical 5% Alcohol-Based Minoxidil Solutions for the Treatment of Androgenetic Alopecia in Indian Men](/images/research/14929182-bad6-426d-94a0-93c5d0e4acb5/small/16451.jpg)
research Comparative Clinical Study Evaluating the Efficacy and Safety of Topical 5% Cetosomal Minoxidil and Topical 5% Alcohol-Based Minoxidil Solutions for the Treatment of Androgenetic Alopecia in Indian Men
Cetosomal minoxidil is safer and as effective as alcohol-based minoxidil for male hair loss treatment.
![Inhibitory Effects of Pueraria mirifica Aqueous Extracts on 5α-reductase and Prostate Histomorphometry in Testosterone-induced Benign Prostatic Hyperplasia Sprague Dawley Rats](/images/research/daaac45d-0113-45ff-ae4b-8c94346f104f/small/36101.jpg)
research Inhibitory Effects of Pueraria mirifica Aqueous Extracts on 5α-reductase and Prostate Histomorphometry in Testosterone-induced Benign Prostatic Hyperplasia Sprague Dawley Rats
Pueraria mirifica extract may help treat benign prostatic hyperplasia.
![Localized Hypotrichosis Type 1 Due to Intragenic Deletion of Exons 5-8 in Desmoglein Gene in a Neonate from Indian Family](/images/research/51e4692a-d98a-4e56-9504-5de180875b37/small/32989.jpg)
research Localized Hypotrichosis Type 1 Due to Intragenic Deletion of Exons 5-8 in Desmoglein Gene in a Neonate from Indian Family
A baby from an Indian family had a rare genetic disorder causing no scalp or body hair due to a specific gene deletion.
![Comparative efficacy of topical finasteride (0.25%) in combination with minoxidil (5%) against 5% minoxidil or 0.25% finasteride alone in male androgenetic alopecia: A pilot, randomized open-label study](/images/research/187249a1-7be0-4296-9f7e-da5cb2359dfa/small/16775.jpg)
research Comparative efficacy of topical finasteride (0.25%) in combination with minoxidil (5%) against 5% minoxidil or 0.25% finasteride alone in male androgenetic alopecia: A pilot, randomized open-label study
Using both minoxidil and finasteride together is more effective for male hair loss than using either one alone.
![PMON281 PERSISTENT VIRILIZATION AND VASOMOTOR SYMPTOMS IN A TRANSMAN 5-YEARS POST TESTOSTERONE WITHDRAWAL](/images/research/e332704d-c360-43f9-95c6-4a4e25ce9cec/small/32695.jpg)
research PMON281 PERSISTENT VIRILIZATION AND VASOMOTOR SYMPTOMS IN A TRANSMAN 5-YEARS POST TESTOSTERONE WITHDRAWAL
A transman experienced lasting virilization symptoms after stopping testosterone, which were resolved with estradiol treatment.
research Disorders of sex development (DSD) 46.XY due to type 2 5-α reductase deficiency in three siblings: Case report from a low-resource setting
Three siblings with a rare genetic condition had abnormal sexual development and chose different gender identities, needing surgery and therapy.
![Structural basis for the catalysis and inhibition of human steroid 5α‐reductase 2](/images/research/1ad5bce5-ac45-4597-9b54-5dd19c3f8c38/small/12049.jpg)
research Structural basis for the catalysis and inhibition of human steroid 5α‐reductase 2
The research gives new understanding on how human steroid 5α-reductases work and how drugs like finasteride inhibit them, which could help in creating new drugs.
research VIBRATIONAL SPECTROSCOPIC INVESTIGATION AND MOLECULAR STRUCTURE OF A 5α-REDUCTASE INHIBITOR: FINASTERIDE
Finasteride's molecular properties and active sites were identified using computational methods.
research Development of Microemulsions<i> </i>Containing<i> Carthamus tinctorius</i> Extract for 5α-Reductase Inhibition
A microemulsion with Carthamus tinctorius extract effectively inhibits 5α-reductase and improves skin and hair follicle delivery.
research Enzyme Inhibitory Activities of Marine Sponges Against Cholinesterase and 5α-Reductase
Marine sponges from Tabuhan Island can inhibit enzymes linked to Alzheimer's and hair loss.
![The Efficacy of Ostrich Antibodies to Dihydrotestosterone and 5<i>α</i>-Reductase in the Restoration of Hair Growth](/images/research/c9df9041-adf3-47d6-8e91-9dceb493b21b/small/13375.jpg)
research The Efficacy of Ostrich Antibodies to Dihydrotestosterone and 5<i>α</i>-Reductase in the Restoration of Hair Growth
Ostrich antibodies can help restore hair growth in people with a specific type of hair loss, increasing hair count by 71% on average.
![The skin findings of pregnant women and our treatment choices. A Turkish experience: a 5-year survey.](/images/research/5bc4b6f1-34ec-4c90-ba40-3204b77387a6/small/24282.jpg)
research The skin findings of pregnant women and our treatment choices. A Turkish experience: a 5-year survey.
Turkish pregnant women commonly experienced skin issues like itching and acne, and doctors mainly used topical treatments due to safety concerns during pregnancy.
research Study on Expression of Insulin-like Growth Factor-binding Protein-3and -5(IGFBP-3 and IGFBP-5)in the Skin of Inner Mongolia Cashmere Goat
![Re: Effect of Testosterone Supplementation With and Without a Dual 5α-Reductase Inhibitor on Fat-Free Mass in Men with Suppressed Testosterone Production: A Randomized Controlled Trial](/images/research/0511a839-670e-46c9-a59a-15bfc6a22458/small/14597.jpg)
research Re: Effect of Testosterone Supplementation With and Without a Dual 5α-Reductase Inhibitor on Fat-Free Mass in Men with Suppressed Testosterone Production: A Randomized Controlled Trial
Testosterone increases muscle mass regardless of DHT conversion blocking.
research Comparison of the Efficacy and Safety of Topical 5% Minoxidil Solution Alone and in Combination with 0.05% Betamethasone Dipropionate Cream in the Treatment of Alopecia Areata
![Patent Evaluation: Δ-4,6-Steroids as Potent 5α-Reductase Inhibitors](/images/research/12d5ebe3-2090-4394-b918-8c5199fa0e42/small/21114.jpg)
research Patent Evaluation: Δ-4,6-Steroids as Potent 5α-Reductase Inhibitors
New steroids were patented as effective for treating acne, hair loss, and other conditions related to hormones.