TLDR Once-daily 5% minoxidil foam and twice-daily 2% minoxidil solution are similarly effective and safe for female pattern hair loss.
The study compared the efficacy and safety of once-daily 5% minoxidil topical foam (MTF) to twice-daily 2% minoxidil topical solution (MTS) in treating female pattern hair loss. In a randomized, phase III trial involving 322 women, the primary endpoint was the change in target area hair count (TAHC) at 24 weeks. Results showed that 5% MTF increased TAHC by 23.9 ± 2.1 hairs/cm², while 2% MTS increased TAHC by 24.2 ± 2.1 hairs/cm². The treatment difference was -0.3 hairs/cm², with a 95% confidence interval of -6.0 to 5.4, failing to meet the noninferiority criteria. Both treatments were well tolerated, but the noninferiority goal was not achieved.
1 citations,
August 2022 in “JAAD case reports” Tofacitinib and oral minoxidil may help treat Sisaipho alopecia areata.
3 citations,
June 2022 in “Dermatology and therapy” A new botanical treatment improved hair growth and symptoms in lichen planopilaris patients.
March 2021 in “Postepy Dermatologii I Alergologii” Minoxidil works equally well for hair growth regardless of scalp blood flow.
25 citations,
June 2018 in “Clinical and Experimental Dermatology” Combined microneedling and minoxidil improves hair growth more than minoxidil alone.
1 citations,
July 2016 in “PubMed” Once-daily 5% minoxidil foam and twice-daily 2% minoxidil solution are similarly effective and safe for female pattern hair loss.
1 citations,
July 2016 in “PubMed” 5% minoxidil foam is effective and safe for hair regrowth in women with hair loss.
100 citations,
June 2011 in “Journal of The American Academy of Dermatology” 5% minoxidil foam once daily works as well as 2% minoxidil solution twice daily for female hair growth and is more convenient.
21 citations,
January 2007 in “Australasian Journal of Dermatology” Spironolactone and minoxidil together effectively treat female pattern hair loss.
1 citations,
September 2002 in “PubMed” Minoxidil helps stimulate hair growth and reduce hair loss in women with androgenic alopecia.
