TLDR Once-daily 5% minoxidil foam and twice-daily 2% minoxidil solution are similarly effective and safe for female pattern hair loss.
The study compared the efficacy and safety of once-daily 5% minoxidil topical foam (MTF) to twice-daily 2% minoxidil topical solution (MTS) in treating female pattern hair loss. In a randomized, phase III trial involving 322 women, the primary endpoint was the change in target area hair count (TAHC) at 24 weeks. Results showed that 5% MTF increased TAHC by 23.9 ± 2.1 hairs/cm², while 2% MTS increased TAHC by 24.2 ± 2.1 hairs/cm². The treatment difference was -0.3 hairs/cm², with a 95% confidence interval of -6.0 to 5.4, failing to meet the noninferiority criteria. Both treatments were well tolerated, but the noninferiority goal was not achieved.
1 citations
,
August 2022 in “JAAD case reports” Tofacitinib and oral minoxidil may help treat Sisaipho alopecia areata.
3 citations
,
June 2022 in “Dermatology and therapy” A new botanical treatment improved hair growth and symptoms in lichen planopilaris patients.
March 2021 in “Postepy Dermatologii I Alergologii” Minoxidil works equally well for hair growth regardless of scalp blood flow.
25 citations
,
June 2018 in “Clinical and Experimental Dermatology” Combined microneedling and minoxidil improves hair growth more than minoxidil alone.
1 citations
,
July 2016 in “PubMed” Once-daily 5% minoxidil foam and twice-daily 2% minoxidil solution are similarly effective and safe for female pattern hair loss.
1 citations
,
July 2016 in “PubMed” 5% minoxidil foam is effective and safe for hair regrowth in women with hair loss.
100 citations
,
June 2011 in “Journal of The American Academy of Dermatology” 5% minoxidil foam once daily works as well as 2% minoxidil solution twice daily for female hair growth and is more convenient.
21 citations
,
January 2007 in “Australasian Journal of Dermatology” Spironolactone and minoxidil together effectively treat female pattern hair loss.
1 citations
,
September 2002 in “PubMed” Minoxidil helps stimulate hair growth and reduce hair loss in women with androgenic alopecia.
