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Propylene glycol and ethanol increase finasteride skin absorption, sodium lauryl sulfate doesn't.

Finasteride helps hair growth but may cause sexual side effects and depression.

Finasteride metabolites found in pigs match human studies, making pigs a valid model for human drug research.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

Stopping finasteride and closing PFO can help prevent strokes in young adults.

Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

Dihydrotestosterone (DHT) stops hair growth in mice by lowering a growth factor important for hair.

PCOS is a complex disorder managed by treating symptoms and requires a team of specialists.

Finasteride and dutasteride reduce neurosteroid production, possibly helping treat glioblastoma.

Minoxidil effectively treats hair loss, especially androgenetic alopecia, but needs more research for better understanding.

Finasteride worsens stress effects on sensory processes, possibly linking to anxiety/depression.

Hair density and thickness decrease in all scalp areas for East Asians with AGA.

Ciproterone acetate improves hair regrowth and acne in most female patients.

The most effective treatments for hair loss are minoxidil, finasteride, PRP, and hair transplants, with steroids and immunosuppressants for autoimmune types.

Some plants may help with hair growth and have fewer side effects than synthetic drugs, but more research is needed to confirm their effectiveness.

Alternative treatments show promise for hair growth beyond traditional methods.

Early balding, especially frontal, increases prostate cancer risk; more research needed.

Animal models, especially mice, are essential for advancing hair loss research and treatment.

Up to 50% of women may experience significant hair loss by age 50, with various causes and treatments available.

Combining synthetic and herbal treatments may help with hair loss, but more research is needed.

Certain Prakruti types are more prone to early male pattern baldness.

Various medicinal plants like Polygonum multiflorum, Red ginseng extract, and Zizyphus jujuba can potentially treat hair loss, offering benefits like low cost and multiple ways of working. Other effective natural substances include Pygeum africanum, Seneroa, Urtica dioica, and more.

Tissue engineering could be a future solution for hair loss, but it's currently expensive, complex, and hard to apply in real-world treatments.

Plant extracts can help prevent hair loss and promote hair growth.

KDML105 bran extract may help with hair growth and prevent hair loss.

Cannabidiol shows promise as an effective treatment for acne.

Trichoscopy shows hair diameter variability, vellus hairs, and the peripilar sign are key indicators for diagnosing Androgenetic Alopecia.