research Sanguisorba Officinalis Root Extract Has FGF-5 Inhibitory Activity and Reduces Hair Loss by Prolonging the Anagen Period
Great Burnet extract may prevent hair loss by extending the hair growth phase.
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research A 5-Year Retrospective Study on Alopecia in a Tertiary Hospital in Southern Nigeria
The most common causes of hair loss in a Nigerian hospital were discoid lupus erythematosus of the scalp and alopecia areata, and more research is needed to understand and address these issues.
research Acute Dermal and Ocular Irritation Testing of Rice Bran Supercritical CO2 Extract (RB-SCE) and 0.5% RB-SCE Essence Product
Rice bran extract caused moderate skin irritation but no eye irritation, while a diluted essence was not irritating to skin and only slightly to guinea pigs.
research A Pilot Study of the Efficacy in Treatment of Female Pattern Hair Loss Using 5% Minoxidil Solution Combined with Oral Chelated Zinc Supplement
Using 5% Minoxidil solution with oral chelated zinc supplement can effectively treat female pattern hair loss.
research Regulatory Effects of Thai Rice By-Product Extracts from Oryza Sativa L. Cv. Bue Bang 3 CMU and Bue Bang 4 CMU on Melanin Production, Nitric Oxide Secretion, and Steroid 5α-Reductase Inhibition
BB4CMU rice bran oil may help treat hair loss and gray hair.
research Antiandrogenic Activity of Riboflavin 5′-Phosphate (FMN) in 22Rv1 and LNCaP Human Prostate Cancer Cell Lines
Riboflavin 5′-phosphate (FMN) shows potential for treating androgen-related conditions but may be limited in treating prostate cancer.
research A Comparative Study of Efficacy of 5% Minoxidil and 5% Minoxidil Plus Platelet-Rich Plasma in the Same Patient for Treatment of Androgenetic Alopecia
Combining 5% minoxidil with platelet-rich plasma is more effective for hair loss than minoxidil alone.
research Case 5: A Very Tall 7-Year-Old Boy with Medulloblastoma
A 7-year-old boy with a brain tumor developed early puberty, which was successfully treated with medication.
research A Narrowed Look Into Plant-Derived Testosterone 5α-Reductase Inhibitors for Androgenetic Alopecia
Plant-based treatments might help with hair loss and have fewer side effects than synthetic drugs.
research Low-Level Light Therapy Versus Topical 5% Minoxidil in the Management of Androgenetic Alopecia in Males: A Randomized Controlled Trial
Both low-level light therapy and 5% minoxidil are effective and safe for treating male hair loss, with no significant difference in results.
research Topical 5% Minoxidil Versus Combined Erbium YAG Laser and Topical 5% Minoxidil in Androgenetic Alopecia: A Randomized Controlled Trial
Using a laser with minoxidil was more effective for hair loss than minoxidil alone.
research A Role for Steroid 5 Alpha-Reductase 1 in Vascular Remodeling During Endometrial Decidualization
The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.
research Structural Basis for the Catalysis and Inhibition of Human Steroid 5α-Reductase 2
The research gives new understanding on how human steroid 5α-reductases work and how drugs like finasteride inhibit them, which could help in creating new drugs.
research Clinical Efficacy, Cosmetic Acceptability, and Local Tolerability of a New Formulation of Topical 5% Minoxidil Without Propylene Glycol: A 6-Month, Multicentre, Real-Life, Prospective, Assessor-Blinded Study in 196 Subjects with Hair Loss. The NOMINAL Trial
The new 5% minoxidil formulation without propylene glycol effectively promotes hair growth with fewer side effects and better user satisfaction.
research Attenuation of 5α-Reductase-Mediated Progesterone Metabolism Promotes Differentiation of Human Endometrial Stromal Cells for the Establishment of Pregnancy
Reducing 5α-reductase activity helps endometrial cells differentiate, aiding pregnancy.
research Case 5
The cat had a rare condition linked to cancer, leading to its euthanasia.
research Importance of Islet Intracrinology for Glucose-Stimulated Insulin Secretion in Males
Androgens and estrogens are crucial for insulin secretion in males.
research Strengthening Hair with Centella Asiatica: A Report of Clinical and Subjective Efficacy of a Local Treatment with a 0.5% Hair Lotion
A lotion with Centella asiatica extract reduced hair loss by 41% and increased hair strength without side effects.
research Circumscribed Juvenile Pityriasis Rubra Pilaris in a 5-Year-Old Girl Treated with Topical Keratolytic and Steroid
A 5-year-old girl with a rare skin disorder was effectively treated with skin creams instead of oral medication.
research Comparative Study of the Insect Repellency Action of Over-the-Counter Herbal Insect Repellent Lotions Against 7.5% DEET Lotion
7.5% DEET lotion is more effective and safe at repelling mosquitoes than rosemary, citronella, and lemongrass lotions.
research A Comparative Study Between the Efficacy and Safety of 5% Minoxidil Solution and 5% Minoxidil Milky Lotion in the Treatment of Male Androgenic Alopecia
Both 5% minoxidil solution and milky lotion effectively and safely treat male hair loss, with the lotion being a good alternative for those sensitive to certain ingredients.
research Tamoxifen-Associated Hirsutism: An Unusual Side Effect in a 5-Year-Old Girl with McCune-Albright Syndrome
A 5-year-old girl with McCune-Albright syndrome grew abnormal hair due to the drug tamoxifen.
research Study on Expression of Insulin-like Growth Factor-binding Protein-3 and -5 (IGFBP-3 and IGFBP-5) in the Skin of Inner Mongolia Cashmere Goat
IGFBP-5 likely plays a key role in goat hair growth.
research Effect of Testosterone Supplementation With and Without a Dual 5α-Reductase Inhibitor on Fat-Free Mass in Men with Suppressed Testosterone Production: A Randomized Controlled Trial
Testosterone increases muscle mass regardless of DHT conversion blocking.
research Association of Breast Cancer in Men with Exposure to 5-Alpha Reductase Inhibitors: A RADAR Report
Taking 5-alpha reductase inhibitors might be linked to breast cancer in men.
research The Relationship Between the Expression of Cytokeratin 5/6 and Clinicopathologic Factors in Invasive Breast Carcinoma
CK 5/6 expression in breast cancer is linked to negative hormone receptor status and higher tumor grade.
research Open Multicenter Clinical Study of 5% Minoxidil Topical Solution in Patients with Androgenetic Alopecia (Phase 4 Clinical Trial) (Joint Study by the Korean Society for Hair Research)
Topical 5% minoxidil is safe and effective for treating hair loss in Korean men.
research Evaluation of Topical Sodium Valproate-Loaded Nano Spanlastics Formulation Versus Minoxidil 5% in the Treatment of Female Pattern Hair Loss Using Transdermal Delivery: A Comparative Study
Topical Valproic acid and 5% Minoxidil both significantly increase hair count in Female Pattern Hair Loss, with similar side effects.
research Caffeic Acid N-[3,5-Bis(Trifluoromethyl)Phenyl] Amide as a Non-Steroidal Inhibitor for Steroid 5α-Reductase Type 1 Using a Human Keratinocyte Cell-Based Assay and Molecular Dynamics
Compound 4 is a promising treatment for hair loss with low toxicity.
research Dermoscopic Evaluation of the Efficacy of Combination of Topical Spironolactone 5% and Minoxidil 5% Solutions in the Treatment of Androgenetic Alopecia, Comparative Study
Combining 5% spironolactone and 5% minoxidil is safe and more effective for treating hair loss.