research Effects of In Utero Exposure to Finasteride on Androgen-Dependent Reproductive Development in Male Rats
Exposure to finasteride in the womb caused lasting reproductive issues in male rats.
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research Genotoxicity of Rice Bran Oil Extracted by Supercritical CO2 Extraction
Rice bran oil extracted by supercritical CO2 is considered non-genotoxic.
research Targeted Transfollicular Delivery of Artocarpin Extract from Artocarpus Incisus by Means of Microparticles
Microparticles containing artocarpin extract could effectively treat hair loss and acne with minimal side effects.
research Clinical Observation of Polycystic Ovary Syndrome Treatment with Resveratrol
Resveratrol improved hormone levels, menstrual cycles, hair loss, and ovarian function in PCOS patients.
research Inhibition of Rat 5α-Reductase Activity and Testosterone-Induced Sebum Synthesis in Hamster Sebocytes by an Extract of Quercus Acutissima Cortex
An extract from Quercus acutissima bark was found to reduce sebum production and block an enzyme linked to acne.
research Prooxidant And Antioxidant Action Of 4-(4-Phenoxybenzoyl)benzoic Acid Derivatives
4-(4-Phenoxybenzoyl)benzoic acid derivatives can both increase and decrease certain types of reactive oxygen species, and may be relevant to hair loss.
research Caffeic Acid N-[3,5-Bis(Trifluoromethyl)Phenyl] Amide as a Non-Steroidal Inhibitor for Steroid 5α-Reductase Type 1 Using a Human Keratinocyte Cell-Based Assay and Molecular Dynamics
Compound 4 is a promising treatment for hair loss with low toxicity.
research Clinical Dose Ranging Studies with Finasteride, a Type 2 5α-Reductase Inhibitor, in Men with Male Pattern Hair Loss
Finasteride effectively treats male pattern hair loss with a 1 mg daily dose.
research Interconnected Polymers Technology (IPSTiC): An Effective Approach for the Modulation of 5α-Reductase Activity in Hair Loss Conditions
A new anti-baldness patch effectively treats hair loss by blocking enzymes linked to the condition.
research Oral Ivermectin in the Treatment of Scabies
Oral ivermectin effectively cured scabies with minimal side effects, and finasteride promoted hair growth in men with hair loss.
research Effect of Finasteride on the Ovulatory Function of Normal Women
Finasteride doesn't affect ovulation in normal women.
research Quantitative Models for the Study of Hair Growth In Vivo
The conclusion is that small hair follicles cause baldness in macaques, and treatments like antiandrogens and minoxidil can prevent hair loss and promote regrowth.
research Effects of Lespedeza Cuneata Aqueous Extract on Testosterone-Induced Prostatic Hyperplasia
Lespedeza cuneata extract may help treat enlarged prostate.
research Effects of PNU157706, a Dual 5α-Reductase Inhibitor, on Rat Epididymal Sperm Maturation and Fertility
PNU157706 reduced rat sperm movement and fertility without affecting offspring health.
research Neuroactive Gonadal Drugs for Neuroprotection in Male and Female Models of Parkinson's Disease
Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.
research Frontal Fibrosing Alopecia: A Retrospective Review of 19 Patients Seen at Duke University
Dutasteride may help stabilize Frontal Fibrosing Alopecia, but more research is needed.
research Vibrational Spectroscopic Investigation and Molecular Structure of a 5α-Reductase Inhibitor: Finasteride
Finasteride's molecular properties and active sites were identified using computational methods.
research Enhanced Follicular Delivery of Finasteride to Human Scalp Skin Using Heat and Chemical Penetration Enhancers
Heat and chemicals improve finasteride delivery to scalp and hair follicles, potentially enhancing treatment for hair loss.
research Male Pattern Hair Loss: Current Understanding
Genetics and hormones cause hair loss; finasteride treats it safely.
research Post-Finasteride Syndrome: Risks and Side Effects of Finasteride for Androgenetic Alopecia
Finasteride may cause lasting sexual, mental, and physical symptoms; use with caution.
research Phase-Specific Differential Regulation of Mechanical Allodynia in a Murine Model of Neuropathic Pain by Progesterone
Progesterone initially worsens but later reduces neuropathic pain in mice, through different mechanisms.
research Steroid Biomarkers and Genetic Studies Reveal Inactivating Mutations in Hexose-6-Phosphate Dehydrogenase in Patients with Cortisone Reductase Deficiency
Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.
research Triple Hormonal Blockade (ADT3): A Patient’s Perspective
Triple Hormonal Blockade (ADT3) can effectively manage prostate cancer but requires careful monitoring for heart risks.
research The Impact of the 5α-Reductase Inhibitors on Male Sexual Function and Psychological Well-Being
5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.
research Effects of Finasteride on Chronic and Acute Ethanol Withdrawal Severity in the WSP and WSR Selected Lines
Finasteride reduces alcohol withdrawal severity and anxiety in mice, but may increase withdrawal severity in some cases.
research Promotion Effect of Constituents from the Root of Polygonum Multiflorum on Hair Growth
Compounds from Polygonum multiflorum root, especially a new one, can boost hair growth more effectively than common treatments.
research SRD5A3 Is Required for Converting Polyprenol to Dolichol and Is Mutated in a Congenital Glycosylation Disorder
Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.
research Clinical Review 74: Dermatological Manifestations of Endocrine Disorders
Skin changes can indicate hormonal imbalances and help diagnose endocrine disorders.
research Improvement in Androgenetic Alopecia in 53-76-Year-Old Men Using Oral Finasteride
Finasteride increases hair count in middle-aged and elderly men without causing sexual dysfunction.
research Effects of In Utero Exposure to D-004, a Lipid Extract from Roystonea Regia Fruits, in the Male Rat: A Comparison with Finasteride
D-004 may be a natural alternative to finasteride for treating enlarged prostate and male baldness.