November 2022 in “Research Square (Research Square)” Topical minoxidil 5% is better for treating female pattern hair loss than topical sildenafil 1%.
February 2022 in “Journal of Cosmetic Dermatology” Using both minoxidil and flutamide together is more effective for treating hair loss than using minoxidil alone.
January 2022 in “The Egyptian Journal of Hospital Medicine” Combining fractional laser with minoxidil 5% is more effective for treating male hair loss than using minoxidil 5% alone.
January 2021 in “Asian Journal of Research in Dermatological Science” January 2020 in “프로그램북(구 초록집)” The treatment increased hair growth and thickness in patients with hair loss.
January 2020 in “Global dermatology” Iontophoresis with a growth factor cocktail helps hair growth in patients with androgenetic alopecia.
January 2020 in “Global dermatology” The growth factor cocktail significantly increased hair growth in patients with androgenetic alopecia.
October 2019 in “International Journal of Research in Dermatology” Combining minoxidil and spironolactone is more effective for female hair loss, but minoxidil alone is sufficient after 6 months.
September 2019 in “Case medical research” January 2019 in “Dermatologica Sinica” Dutasteride improved both hair loss and acne in two young men.
September 2016 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Once-daily 5% minoxidil foam increases hair regrowth and density in women with hair loss, but not as effectively as twice-daily 2% minoxidil solution, though it's safer and more convenient.
January 2009 in “Journal of Pakistan Association of Dermatology” Systemic cyproterone acetate and 5% topical minoxidil are effective and safe for treating female pattern hair loss.
408 citations,
May 2004 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Dutasteride more effectively lowers DHT levels in men with enlarged prostates than finasteride.
211 citations,
November 1990 in “The Journal of Steroid Biochemistry and Molecular Biology” Finasteride effectively treats BPH, but needs more trials to understand potential.
184 citations,
January 2000 in “European Urology” Blocking the enzyme that turns testosterone into DHT can safely and effectively treat enlarged prostate.
101 citations,
March 1987 in “Journal of The American Academy of Dermatology” Minoxidil solution helps hair regrowth in alopecia areata, with 5% being more effective.
75 citations,
June 2007 in “Journal of Biological Chemistry” The study demonstrated that MT-DADMe-ImmA, a potent inhibitor of MTAP, effectively induced apoptosis in head and neck cancer cell lines FaDu and Cal27 by increasing MTA levels and decreasing polyamines, leading to mitochondrial changes and activation of caspases. This treatment selectively targeted cancer cells without affecting normal fibroblasts, suggesting its potential as a cancer treatment. In a mouse model, MT-DADMe-ImmA led to tumor remission, highlighting its promise for cancers sensitive to DNA methylation changes. Despite inducing apoptosis, the treatment did not alter the protein levels of mitochondrial markers Bcl2 and Bax.
75 citations,
November 1996 in “Fertility and Sterility” Finasteride effectively reduces hair growth in women with idiopathic hirsutism, but requires careful contraception during treatment.
66 citations,
June 2013 in “Journal of Dermatological Treatment” Finasteride and dutasteride effectively treat hair loss, but may cause side effects like sexual dysfunction and depression.
54 citations,
January 2005 in “Journal of The American Academy of Dermatology” Most patients with chronic hair shedding did not progress to permanent hair loss, and one showed improvement with treatment.
53 citations,
August 2019 in “Journal of The American Academy of Dermatology” Oral minoxidil and topical minoxidil 5% both effectively improve female-pattern hair loss with safe side effects.
51 citations,
October 2002 in “European journal of endocrinology” Low-dose finasteride effectively treats hirsutism, is safe, and cost-effective.
48 citations,
November 1992 in “Clinical Endocrinology” Long-term finasteride use doesn't change bone density or metabolism.
47 citations,
April 2003 in “Journal of dermatological science” Thujae occidentalis semen extract may help treat male pattern baldness by blocking a hair loss-related enzyme and reducing hair loss in mice.
47 citations,
January 2001 in “Journal of Investigative Dermatology” High testosterone to epitestosterone ratio in hair could predict male-pattern baldness.
44 citations,
January 1997 in “British Journal of Dermatology” 
39 citations,
April 2007 in “Therapeutic Drug Monitoring” Finasteride affects urinary steroid profiles and can potentially hide steroid abuse in sports drug testing.
37 citations,
January 1991 in “Reproductive Toxicology” Finasteride reduces male rat fertility by causing issues with copulatory plug formation.
35 citations,
October 2011 in “Medicine and science in sports and exercise” Muscles can make their own androgens, which may help muscle growth.