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research Multidomain Peptide Hydrogel Accelerates Healing of Full-Thickness Wounds in Diabetic Mice
This study found that MDP hydrogel significantly accelerated wound healing and improved tissue formation in diabetic mice compared to a standard clinical hydrogel and control buffer.
research 362 Not just a cell marker: DPP4 modulates regeneration of hair follicles in large wounds
This study found that inhibiting DPP4 during a critical period post-wounding increases hair follicle regeneration and Wnt signaling in large skin wounds.
research Corrigendum to ‘3D bioprinting of a gelatin-alginate hydrogel for tissue-engineered hair follicle regeneration’ [Acta Biomaterialia (2022)]
Corrections were made to a previous work on 3D printing a gel-alginate mix for creating hair follicles, but the main finding - that this method can help grow hair - remains the same.
research Innovations in skin microphysiological systems for nonclinical testing and FDA modernization
This review discusses advancements in skin microphysiological systems, such as 3D bioprinting, skin organoids, and skin-on-a-chip, and their effectiveness in emulating human skin functions for research and preclinical applications, highlighting the potential for replacing animal testing with these innovative technologies.
research 924 Efficient genome editing using CRISPR/Cas9 ribonucleoprotein approach in iPS cells for recessive dystrophic epidermolysis bullosa
This study demonstrated that gene-corrected 3D skin constructs from RDEB patient-derived iPSCs, grafted onto immunocompetent mice, showed normal collagen VII expression after two months.
research The Three-Dimensional Human Skin Reconstruct Model: a Tool to Study Normal Skin and Melanoma Progression
This review discusses the development and findings of 3D human skin models for studying melanocyte homeostasis and melanoma progression but reports no new clinical results.
research Randomized Controlled Trial Study to Evaluate the Efficacy of Combination Therapy with Diphenylcyclopropenone and Platelet-Rich Plasmain Alopecia Areaata
This study found that adding PRP to DPCP treatment for severe alopecia areata did not enhance effectiveness compared to DPCP alone.
research TGF‐β2 is specifically expressed in human dermal papilla cells and modulates hair folliculogenesis
This study suggests that TGF-β 2 plays a critical role in hair follicle morphogenesis and may enhance the effectiveness of future cell therapies for hair regrowth using expanded dermal papilla cells.
research CD133 defines hair-inductive cells in the dermal papilla
This study found that CD133-positive dermal papilla cells significantly enhanced hair growth in mice compared to CD133-negative cells, suggesting their potential for improving human hair follicle engineering.
research 3D Spheroid Human Dermal Papilla Cell as an Effective Model for the Screening of Hair Growth Promoting Compounds: Examples of Minoxidil and 3,4,5-Tri-O-caffeoylquinic acid (TCQA)
3D spheroid cells effectively test hair growth compounds like Minoxidil.
research Engineering Spatially Organized Hair Peg-like Structures in Human Skin Constructs Using Keratinocyte–Dermal Papilla Fibroblast Spheroids and Micropatterned Dermal Scaffolds
This study introduced a bioengineering platform that creates early-stage hair peg-like structures within tissue-engineered skin substitutes by integrating human keratinocytes and dermal papilla cells with laser-micropatterned collagen scaffolds, providing a foundation for future appendage-inclusive skin regeneration efforts.
research Advances in 3D Printed Bone Implants: Smart Responsive Antibacterial Strategies and AI-Driven Design
This review discusses recent advancements in bone tissue engineering, emphasizing a shift from passive to smart responsive antibacterial strategies to prevent implant-associated infections, and highlights AI's role in optimizing bone scaffold design for personalized, infection-free implants.
research Scaffold-Assisted Artificial Hair Implantation in a Rat Model
This study found that both PHDPE and ePTFE hair-bearing scaffolds were well tolerated in a rat model, with minimal infection or extrusion, though artificial hair showed progressive loss over time.
research Establishment of an immortalized mouse dermal papilla cell strain with optimized culture strategy
This study successfully optimized a culture strategy for dermal papilla cells and established an immortalized cell strain, iDP6, which is suitable for research and application.
research 利用地面光達點雲建置三維房屋模型;Reconstructing 3D Building Model from Terrestrial LiDAR Point Cloud
This study found that in beagles with benign prostate hyperplasia, finasteride treatment increased blood volume and decreased vessel leakiness in the prostate's parenchymal zone as shown by dynamic contrast-enhanced MRI.
research 17 Procedural Hair Restoration: Platelet-Rich Plasma for Hair Loss and Hair Transplant procedural hair restoration platelet-rich plasma (PRP) for hair loss and hair transplant
This chapter reviews procedural hair restoration techniques, including platelet-rich plasma and hair transplantation, and reports no new clinical findings.
research Polydeoxyribonucleotides – the future of regenerative medicine
This article reviews the potential uses of PDRN in regenerative and aesthetic medicine, noting promising results in various treatments but highlighting the need for further long-term studies to confirm their safety and effectiveness.
research 3D-Printed degradable hair follicle hanging drop scaffolds integrated with tissue engineered skin promotes hair follicle regeneration in vitro
This study constructed a 3D-printed scaffold using sodium alginate, gelatin, and alginate lyase hydrogel, which supports hair follicle regeneration in artificial skin, suggesting a promising strategy for tissue-engineered skin with functional appendages.
research Engineering Human Skin with Spatially Defined Hair Peg-Like Structures Using Self-Organizing Composite Organoids and Micropatterned Dermal Scaffolds
research 557 A peptide derivative with known anti-wrinkle properties was identified as potent dipeptiylpeptidase-4 inhibitor
This study found that the peptide derivative beta-Ala-Pro-Dab-NHbenzyl may reduce wrinkles and sebum production in human skin by inhibiting dipeptidyl peptidase 4, suggesting potential for acne and skin inflammation treatment.
research Platelet rich plasma or platelet rich fibrin: which is better in post extraction immediate implant placement followed by immediate loading?
This study concluded that platelet rich fibrin (PRF) may enhance healing and functional recovery compared to platelet rich plasma (PRP) during immediate post-extractive dental implant procedures.
research As a carrier–transporter for hair follicle reconstitution, platelet-rich plasma promotes proliferation and induction of mouse dermal papilla cells
This study found that 5% activated platelet-rich plasma significantly improved cell proliferation and hair-inductive ability of dermal papilla cells in vitro, and promoted hair follicle formation in mice.
research Self-assembly of dermal papilla cells into inductive spheroidal microtissues on poly(ethylene-co-vinyl alcohol) membranes for hair follicle regeneration
This study found that poly(ethylene-co-vinyl alcohol) membranes support the self-assembly of dermal papilla cells into compact spheroidal microtissues capable of inducing new hair follicles, suggesting potential for large-scale production for hair follicle regeneration.
research Hair growth promoting effects of human dermal papilla cells in pig
This study found that a single intradermal injection of human dermal papilla cells increased hair follicle number and thickness in pigs, suggesting potential effectiveness for hair growth in humans.
research Development and Prospective Applications of 3D Membranes as a Sensor for Monitoring and Inducing Tissue Regeneration
This source reviews the potential of 3D printing, biomaterials, and smart sensors in tissue engineering, noting their application in creating artificial membranes for skin and tissue regeneration and assessing their strengths and limitations for wound dressing development and disease modeling.
research Coupled 3D reconstruction of sparse facial hair and skin
This study presented a new algorithm and camera-based system that successfully reconstruct high-quality, 3D representations of facial hair and underlying skin surfaces even in dense regions like eyebrows.
research A Bilayer Polyurethane/Liquid Metal Dressing with Self-Powered Electrical Stimulation and Dynamic Adhesion for Wound Healing
research Human Derived Immortalized Dermal Papilla Cells With a Constant Expression of Testosterone Receptor
This study developed a DPC cell line by introducing mutant CDK4, Cyclin D1, and TERT, making it a promising tool to study downstream signaling pathways activated by testosterone in androgenetic alopecia.