27 citations
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December 1997 in “Archives of Dermatological Research” This study observed that cultured dermal papilla cells showed distinct functional properties from dermal fibroblasts, including lower proliferation rates, higher adhesion to collagen type IV, and different cell-matrix interactions.
May 2026 in “Biotechnology and Bioengineering” This review discusses recent breakthroughs in 3D bioprinting for hair regeneration, highlighting developments like biomimetic dermal papilla spheroids and follicle organoids, but notes that clinical application is hindered by challenges in integrating vascular and nerve systems and managing hair-cycle dynamics.
1 citations
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June 2003 in “Obstetrical & Gynecological Survey” This new method makes checking for female infertility less painful, less invasive, and doesn't use radiation.
4 citations
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April 2024 in “Cellular and Molecular Biology” In this study, injectable platelet-rich fibrin (i-PRF) was found to enhance the proliferative, migratory, and hair-inducing abilities of dermal papilla cells more effectively than platelet-rich plasma through the TGF-β/Smad pathway.
39 citations
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September 2019 in “Materials & Design” This study developed a new mask-free method using digital micromirror and microfluidic systems to create multicellular heterospheroids for drug screening, finding that heterospheroids exhibit higher drug resistance and combinatorial drugs are more effective than single drugs in cancer therapeutic applications.
August 2025 in “Journal of Polymer Science” This review reports that combining adipose-derived stem cells with decellularized extracellular matrix enhances tissue repair by improving scaffold biological activity and promoting angiogenesis, integration, and functional regeneration across various tissues, while addressing challenges in traditional transplantation methods.
10 citations
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April 2007 in “Aesthetic Plastic Surgery” This study demonstrated the feasibility of a new patient-controlled method for tissue expansion that achieved full expansion in about 3 weeks with minimal complications after mastectomy.
This review discusses how advancements in biomaterial engineering and 3D bioprinting are transforming skin wound-healing therapies, highlighting innovations in bioinks and the evolving global market potential of these technologies for developing next-generation skin substitutes.
8 citations
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December 2017 in “Current Opinion in Cell Biology” This review discusses advances in 3D bioengineering technologies for regenerating complex oral organs and suggests they could play a key role in future organ replacement therapy.
December 2010 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” This entry does not provide an abstract or new research findings, so no specific results are available for summary.
April 2020 in “Rice Research Repository (Rice University)” This study suggests that MultiDomain Peptide hydrogels may support wound healing in diabetic mice by accelerating closure and promoting tissue regeneration, though they did not inhibit bacterial growth in infected wounds as expected.
9 citations
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August 2023 in “Molecules” This study found that the peptides RMYYY and VMYMI displayed stronger binding energy and more frequent interactions with HPGDS compared to the native inhibitor, suggesting potential as future therapeutic drugs.
13 citations
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August 2022 in “Nanomaterials” This study reported that a novel trilayer electrospinning wound dressing can improve the wound microenvironment and accelerate repair in abdominal wall defects by facilitating directional biofluid transport and reducing inflammation.
July 2020 in “CRS 2020 Virtual Annual Meeting” This study found that the newly developed microarray patches for intradermal delivery of finasteride showed high drug content and significantly improved skin deposition compared to existing methods.
1 citations
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October 2021 in “QJM: An International Journal of Medicine” This study found that platelet-rich plasma prepared using a double-spin method may be more effective for treating female pattern hair loss than single-spin PRP, although VEGF concentration was unaffected by either preparation method.
18 citations
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January 2021 in “Theranostics” This study found that actively targeted AN2728-loaded nanocarriers reduced inflammation and improved skin condition in a mouse model of psoriasiform inflammation compared to free drug and non-targeted nanoparticles.
13 citations
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September 2021 in “Frontiers in Cell and Developmental Biology” This study found that suspension culture was more effective than hydrogel-based systems for maintaining spheroid morphology and differentiation of human iPSC-derived definitive endoderm cells.
This study developed a three-dimensional model for studying hair follicle development, showing that immortalized dermal papilla cells retain certain differentiation activities and can induce tubule formation in vitro.
December 2025 in “Anatomy (International Journal of Experimental and Clinical Anatomy)” In this study, researchers found that the congenital absence of the palmaris longus muscle was relatively uncommon and showed no significant differences according to sex, side, or digit ratio (2D:4D) among individuals assessed using MRI and radiographs.
July 2025 in “Journal of Investigative Dermatology” Hhip-Cre effectively targets dermal papilla cells for gene manipulation in hair biology.
58 citations
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March 2019 in “Experimental Dermatology” This study suggests that exosomes derived from dermal papilla cells, especially those cultured in three dimensions, promote hair growth and regeneration by enhancing follicular cell activity.
April 2026 in “Biomedical and Biotechnology Research Journal (BBRJ)” In this study, researchers observed that using microtube-based forced aggregation, human hair follicle dermal papilla cells formed stable, compact spheroids at higher cell densities, showing enhanced expression of specific markers compared to 2D culture.
5 citations
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February 2019 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that extracellular vesicles derived from 3D cultures of cervical cancer cells have small RNA profiles more similar to those in patient plasma than those from 2D cultures.
April 2017 in “Journal of Investigative Dermatology” This study observed that a 3D culture model of hair follicle cells showed an anagen-like phase between days 3 to 6 and transitioned to a catagen-like phase by day 7, highlighting cell differentiation and structural development over time.
1 citations
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June 2012 in “OhioLink ETD Center (Ohio Library and Information Network)” In this study, the 40-MBR system was shown to enhance drug-screening efficiency by providing reliable, real-time monitoring of cell conditions in 3-D cultures compared to traditional methods.
6 citations
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January 2024 in “Annals of Dermatology” In this study, treatment with recombinant DKK2 was shown to significantly stimulate hair progenitor cell growth and enhance hair shaft elongation in ex vivo human hair follicle cultures by activating the Wnt/ẞ-catenin signaling pathway, suggesting a potential role for DKK2 in promoting hair growth.
January 2025 in “Diagnostics” This study found that a new three-dimensional high-frequency ultrasound (3D-HFUS) can successfully visualize skin tumors and inflammatory hair diseases, offering promising noninvasive diagnostic and evaluation capabilities compared to traditional two-dimensional methods.
April 2018 in “Journal of Investigative Dermatology” In this animal study, the researchers found that DPP4 plays a crucial role in scar formation and wound-induced hair follicle neogenesis in mice, impacting regenerative repair.
68 citations
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August 2014 in “Stem Cells Translational Medicine” This study found that composite skin constructs containing dermal papilla cells promoted better skin healing and hair regeneration in nude mice, highlighting their role in tissue-engineered skin for severe injuries.
1 citations
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April 2019 in “Journal of Investigative Dermatology” This study examined the safety and efficacy of dupilumab in adolescents with moderate-to-severe atopic dermatitis, finding that it was well tolerated and significantly improved symptoms over 52 weeks, with its safety profile similar to that in adults.