The Three-Dimensional Human Skin Reconstruct Model: A Tool to Study Normal Skin and Melanoma Progression
August 2011
in “
Journal of Visualized Experiments
”
TLDR 3D human skin models better mimic real skin and melanoma progression than 2D or mouse models.
The three-dimensional human skin reconstruct model was developed to mimic the architecture and composition of human skin, providing a valuable tool for studying normal skin functions, melanoma progression, and the behavior of dermal stem cells. This model allowed researchers to investigate melanocyte physiology and the progression of melanoma in a controlled environment. Additionally, it served as a preclinical tool for assessing the efficacy of drugs, offering insights into potential treatments for skin-related conditions.