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In this study, treatment with the oral contraceptive containing 30 μg ethinyl oestradiol and 150 μg desogestrel significantly reduced androgen-dependent hair growth in hirsute women over one year.

This study generated a pharmacophoric model for both isoforms of steroidal 5α-reductase using 6-azasteroids, providing a structural framework for designing new inhibitors.

In this study, Cyanidin 3-O-arabinoside was found to protect against DHT-induced dermal papilla cell senescence and mitochondrial dysfunction in androgenetic alopecia, restoring hair growth in mouse models.

In a testosterone-induced BPH rat model, this study found that ursolic acid treatment significantly reduced prostate weight and hormone levels, suggesting it may inhibit BPH development.

Hidradenitis suppurativa improves with antiandrogen therapy.

In this study, two different estroprogestin treatments significantly improved skin conditions and decreased androgen levels in hyperandrogenic women, with EE/DRSP showing more pronounced hormonal changes and skin improvements compared to EE/CMA.

This review explores the hormonal factors related to hidradenitis suppurativa, emphasizing insulin resistance and pro-inflammatory adipokines, but reports no new clinical findings and suggests further research is needed.

This study reported that newly synthesized nonsteroidal compounds were effective at inhibiting prostatic 5 alpha reductase isozyme 2, especially the compound with an N, N-diisopropylcarbamoyl substituent, suggesting potential for treating benign prostatic hyperplasia.

This study found that finasteride treatment may decrease contraction of seminal vesicle tissue and alter some semen parameters in male rabbits.

This study found that 5α-reductase inhibitors significantly increase the risk of erectile dysfunction and hypoactive sexual desire in men with benign prostatic hyperplasia, compared to placebo.

In this study, dihydroartemisinin reduced prostate enlargement and related markers in a rat model of benign prostatic hyperplasia, suggesting its potential as a therapeutic agent.

This study introduced a validated LC-MS/MS-based method for profiling long-term steroid concentrations in human scalp hair, offering potential applications in endocrinology research.

This study found that concentrations of haloperidol and its metabolite in human scalp hair significantly correlated with the daily dose and plasma trough levels in patients taking haloperidol.

Finasteride helped treat a 28-year-old's facial skin condition.

This study found that cyproterone acetate, given with ethinyl oestradiol, significantly reduced hirsutism in women after 12 months, although improvements reversed once cyproterone acetate was stopped.

This case report describes a unique instance where elevated prolactin levels from a pituitary adenoma were associated with hirsutism due to increased dihydrotestosterone, with treatment leading to normalization.

In this study, AMP-303 injections demonstrated a trend toward increasing non-vellus hair count in men with mild to moderate androgenetic alopecia, notably showing a 14.5% peak increase at 60 days compared to saline, with effects lasting up to five months.

This study found that DHEA along with osteogenic induction medium significantly promotes the osteogenic differentiation and proliferation of human bone marrow mesenchymal stem cells from older individuals.

In this study, the authors identified the DHRS9 SNP rs72623193 as most significantly associated with response to dutasteride in treating male pattern hair loss, with additional variants potentially contributing.

In this study, patients with testicular feminization syndrome showed limited anabolic responsiveness to dihydrotestosterone, potentially due to reduced affinity of nuclear receptor sites for androgenic steroids rather than defective testosterone conversion.

In this study, chronic finasteride administration in near-term pregnant rats restored baroreflex control of renal sympathetic nerve activity to levels observed in non-pregnant rats.

This study observed that male human hair follicles metabolized dehydroepiandrosterone (DHA) more intensively than skin did and found altered DHA metabolism in follicles from balding individuals.

This study found that finasteride decreased plasma dihydrotestosterone levels and altered steroid metabolism, similar to the profile of male pseudohermaphrodites with inherited 5a-reductase deficiency.

This case report describes the treatment of hirsutism in a 15-year-old obese Mexican girl with flutamide, aiming to improve her social function.

Human hair follicles can process steroid hormones like DHEA.

This study investigated the effects of 5-alpha-reductase inhibitors on penile histomorphometry in both normotensive and hypertensive rats, reporting no significant changes between treated and untreated groups.

In an animal study, researchers observed that a newly synthesized deoxycholic acid derivative showed similar prostate protection effects to finasteride in Wistar rats while being less toxic.

A new compound that could treat various androgen-related conditions was created and analyzed.

This review analyzed past research on hormonal treatments for hidradenitis suppurativa, finding that anti-androgens like finasteride and spironolactone, along with metformin, showed promise but large-scale trials are needed to understand their full potential.

This study suggests 5α‐androstan‐3α‐17β‐diol may be the true inducer of kidney enzymes in certain mice, while its induction mechanism likely involves pinocytosis rather than a receptor protein.