Metabolism of Dehydroepiandrosterone by Isolated Human Hair Follicles

December 1971 in “ European Journal of Endocrinology ”

Á Fazekas

dehydroepiandrosterone DHEA testosterone androstenedione dihydrotestosterone DHT steroid hormones hair follicles enzymatic capability

Studysummary Human hair follicles can process steroid hormones like DHEA.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer ·

Read the full study on doi.org →

Discuss this study in the Community →

Similar research 5

Metabolism of Androgens by Isolated Human Beard Hair Follicles Steroids · 1971
Metabolism of Androgens by Isolated Human Hair Follicles Journal of Steroid Biochemistry · 1972
The Metabolism of Dehydroepiandrosterone by Human Scalp Hair Follicles The Journal of Clinical Endocrinology & Metabolism · 1973
Hydroxylation of Dehydroepiandrosterone in Human Scalp Hair Follicles British Journal of Dermatology · 1979
In Vitro Metabolism of Dehydroepiandrosterone and Testosterone by Canine Hair Follicle Cells Veterinary Dermatology · 2004

Related Community Posts Join

6 / 1000+ results

community DHEA, the culprit behind DUPA ? Read this!

20 upvotes 3 years ago

High DHEA levels may contribute to hair loss by increasing DHT in hair follicles, potentially explaining why finasteride is ineffective for some. Treatments like high-dose dutasteride and RU58841 are suggested, but the underlying cause, such as adrenal issues, should be investigated.

community What hormones should I have tested at a minimum before starting a DHT blocker or anti-androgen?

4 upvotes 2 years ago

The conversation is about someone planning to start finasteride or RU58841 for hair loss and wanting to know which hormones to test beforehand. They found a package for testing testosterone, free testosterone, estradiol, and DHT, and are asking if these tests are enough.

community Estradiol (E2), Testosterone and DHT levels after 1 month on Dutasteride

in Research/Science 11 upvotes 1 year ago

Dutasteride and finasteride are used for hair loss, affecting hormone levels like DHT and testosterone. Hormone balance is crucial, as changes can lead to side effects such as increased estradiol and potential hair loss.

community Thoughts on Pre-Finasteride Bloodwork? Normal/high Total and Free Testosterone, Low DHEA-S?

5 upvotes 4 years ago

A 23-year-old male is considering starting Finasteride for hair loss after experiencing persistent shedding and hairline recession, with bloodwork showing normal testosterone levels but low DHEA-S and Vitamin D. He plans to discuss DHEA supplementation with his doctor and has already started Vitamin D supplementation.

community M-28, did a few hormone blood tests since I want a baseline before starting Fin. DhT high. But also Estradiol? Why?

4 upvotes 5 years ago

A user discusses their hormone blood test results before starting finasteride for hair loss, noting high DHT and estradiol levels. They tried topical finasteride for a few days but felt tired.

community My Estradiol Level on Finasteride

18 upvotes 1 year ago

Finasteride has no effect on the user's estradiol levels, and body fat may influence aromatization. The user is on testosterone replacement therapy and uses everyday injections to manage high RBC count, with plans to measure DHT, DHEA-S, and pregnenolone levels.