Metabolism of Dehydroepiandrosterone by Isolated Human Hair Follicles

The document reported that isolated human hair follicles were capable of metabolizing dehydroepiandrosterone (DHEA). It was found that these follicles could convert testosterone into androstenedione and dihydrotestosterone. This finding suggested that hair follicles had the enzymatic capability to process steroid hormones, which could have implications for understanding hair growth and hair loss mechanisms.