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The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

AGA is a genetic, hormonal hair loss treated with finasteride, minoxidil, and supplements, but new compounds are being developed.

Minoxidil and retinol together help hair grow.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

COVID-19 can cause different skin symptoms that may help with early diagnosis and show how severe the disease is.

Finasteride use changes brain chemicals, causing lasting sexual issues and anxiety/depression.

Nonclassic adrenal hyperplasia is a genetic condition that can cause early puberty and fertility problems, treated with specific steroids.

Finasteride affects alcohol intake in male mice, possibly due to neurosteroids.

Cytokines and neuropeptides are key in controlling androgen levels, affecting skin and hair conditions.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Hidradenitis suppurativa may be related to hormones and patients often have metabolic disorders; more research is needed to understand this connection.

17-β-Estradiol applied to the skin stops hair growth, while ICI 182 780 helps hair grow in mice.

Cyperus rotundus oil effectively reduces unwanted hair without side effects.

Higher DHT in male baldness may protect against prostate cancer.

Androgens can both increase body hair and cause scalp hair loss.

5-alpha reductase inhibitors might worsen lung recovery in COVID-19 patients, suggesting a pause in their use.

Triptorelin helps evaluate hormone production in Sertoli-Leydig cell tumors.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

Polycystic Ovary Syndrome is linked to higher risk of hypertension and heart disease.

Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.

Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

Finasteride reduces new brain cells in male mice, possibly causing depression.

Androgen receptor signaling causes early aging of cells important for hair growth by damaging their DNA.

The document concludes that new treatments are needed to better manage acne and reduce side effects related to current therapies.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Different skin cells process testosterone differently, and certain drugs can change this process, possibly helping treat acne and hair loss.

Botanicals like green tea extract show potential for hair growth, but more research is needed.