research Androgens and Androgen Receptor in the Management of Skin Diseases
Understanding how androgens and their receptors work can lead to improved treatments for skin diseases.
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research Hair Growth Promotion and Anti-Hair Loss Effects of Arabica Coffee Pulp Extracts Using Supercritical Fluid Extraction
Arabica coffee pulp extract may help prevent hair loss and promote hair growth.
research Polycystic Ovary Syndrome: A Comprehensive Review of Pathogenesis, Management, and Drug Repurposing
PCOS management includes lifestyle changes and medications, with ongoing research into repurposed drugs for better treatment options.
research Polycystic Ovary Syndrome and Oxidative Stress: From Bench to Bedside
Oxidative stress worsens PCOS by damaging cells and disrupting metabolism, suggesting antioxidant treatments might help.
research Role of Regeneration in Tissue Repairing and Therapies
The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.
research Pubertal Hormones Increase Hippocampal Expression of α4βδ GABAA Receptors
Hormones during puberty increase certain receptors in the brain, and this change is influenced by estrogen levels.
research Dermatologic Changes in Experimental Model of Long COVID
Mice with a virus similar to COVID-19 had skin damage, but a special treatment helped repair it.
research Whole-Genome Resequencing Reveals Selection Signal Related to Sheep Wool Fineness
Genes linked to wool fineness in sheep have been identified.
research Topical Finasteride: A Comprehensive Review of Androgenetic Alopecia Management for Men and Women
Topical finasteride might be a good alternative for hair loss treatment with fewer side effects, but more research is needed.
research Effect of Neurosteroids on Basal and Stress-Induced Oxytocin Secretion in Luteal-Phase and Pregnant Sheep
Neurosteroids help regulate oxytocin levels, especially during stress and pregnancy, to protect against premature labor.
research The Biological Actions of Dehydroepiandrosterone Involve Multiple Receptors
DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.
research International Society for the Study of Women's Sexual Health Clinical Practice Guideline for the Use of Systemic Testosterone for Hypoactive Sexual Desire Disorder in Women
Testosterone can help premenopausal and postmenopausal women with low sexual desire, but its long-term safety is unclear and it's not widely approved for this use.
research What Does the Research Say About Androgen Use and Cerebrovascular Events?
Androgen use may increase the risk of stroke, but more research is needed.
research The Interplay Between Finasteride-Induced Androgen Imbalance, Endoplasmic Reticulum Stress, Oxidative Stress, and Liver Disorders in Paternal and Filial Generation
Finasteride in male rats causes liver and metabolic issues in their offspring.
research Aldo-Keto Reductase (AKR) 1C3 Inhibitors: A Patent Review
The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.
research A Randomized Placebo-Controlled Study on the Effects of Pioglitazone on Cortisol Metabolism in Polycystic Ovary Syndrome
Pioglitazone improved insulin sensitivity and altered cortisol metabolism in PCOS patients.
research Polycystic Ovary Syndrome and Fertility
PCOS affects fertility and is linked to obesity and menstrual irregularities; lifestyle changes are recommended for treatment.
research A Comprehensive Review of Acne Vulgaris
Acne can't be cured but can be managed with treatments like benzoyl peroxide and diet changes; it's costly and can lead to scarring and mental health issues.
research The Mechanisms and Management of Age-Related Oxidative Stress in Male Hypogonadism Associated with Non-Communicable Chronic Disease
Managing oxidative stress might help treat low testosterone and related chronic diseases in aging men.
research Integrin Beta 1 Establishes Liver Microstructure and Modulates Transforming Growth Factor Beta During Liver Development and Regeneration
Integrin β1 is crucial for liver structure and function, preventing fibrosis.
research Endocrine Functions of the Testes
The testes produce important hormones like testosterone and others that play key roles in male body functions.
research Pregnenolone for the Treatment of L-DOPA-Induced Dyskinesia in Parkinson's Disease
Pregnenolone might help manage movement issues caused by Parkinson's disease treatment without reducing the medicine's effectiveness.
research Post-Finasteride Syndrome and Post-SSRI Sexual Dysfunction: Two Clinically Similar Conditions
Some people experience lasting sexual, psychological, and sleep problems after using finasteride or SSRI antidepressants, possibly due to similar underlying causes.
research Rare and Underappreciated Causes of Polycystic Ovarian Syndrome
Some lesser-known causes of PCOS include autoimmune issues, genetic mutations, and changes in the body's microbiome.
research Reprogramming Adult Dermis to a Neonatal State Through Epidermal Activation of Beta-Catenin
Activating a protein called β-catenin in adult skin can make it behave like young skin, potentially helping with skin aging and hair loss.
research Androgens and Ovarian Function: Translation from Basic Discovery Research to Clinical Impact
Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.
research Inhibitors of 5α-Reductase-Related Side Effects in Patients Seeking Medical Care for Sexual Dysfunction
5α-reductase inhibitors may worsen sexual drive and spontaneous erections but don't worsen existing erectile or ejaculatory problems.
research HSD3B1 Gene Polymorphism and Female Pattern Hair Loss in Women with Polycystic Ovary Syndrome
HSD3B1 gene variant and being overweight linked to hair loss in women with polycystic ovary syndrome.
research Sebocytes Are the Key Regulators of Androgen Homeostasis in Human Skin
Sebocytes play a key role in controlling androgen levels in human skin.
research Intratumoral De Novo Steroid Synthesis Activates Androgen Receptor in Castration-Resistant Prostate Cancer and Is Upregulated by Treatment with CYP17A1 Inhibitors
Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.