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Targeting the Smoothened receptor shows promise for treating certain cancers.

The document concludes that treating female hair loss should target reducing excess androgen and blocking its effects on hair follicles, with the best treatments being hormonal therapy, adrenal suppression, and topical minoxidil.

Spironolactone is better than placebo for reducing excessive hair growth in women, but its effectiveness for acne is unclear due to small study sizes.

Fat cells are important for tissue repair and stem cell support in various body parts.

Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.

Men are more likely to have severe respiratory viral infections like COVID-19 due to hormonal and genetic differences, while women generally have stronger immune responses.

Anthralin is effective for psoriasis and alopecia with minimal systemic side effects but can irritate the skin.

Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

Anti-androgens are safe and effective for treating moderate to severe adult female acne.

Pediatric endocrinologists should provide early fertility counseling and preservation options to young patients at risk of infertility.

Reductive stress messes up collagen balance and alters cell signaling in human skin cells, which could help treat certain skin diseases.

Excessive hair growth in women can be harmless or signal serious health issues, and treatment often includes medication and hair removal, with noticeable results after 3-6 months.

The document concludes that managing PCOS involves treating symptoms and reducing long-term metabolic risks, with lifestyle changes being important.

Genetic changes in mice help understand skin and hair disorders, aiding treatment development for acne and hair loss.

Most women with hirsutism or androgenic alopecia had polycystic ovaries, especially if they had irregular periods.

Graphene oxide and indole-3-acetic acid together inhibit root growth in Brassica napus L. by affecting multiple plant hormone pathways.

An 11-year-old boy in Saudi Arabia has a rare case of hypoparathyroidism with severe brain calcifications but normal development and no known cause.

The FRZB gene slows hair growth in rabbits.

Female rats showed more panic-related behavior than males, influenced by hormonal cycles and certain drugs.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

ΔNp63α helps control a protein that stops cancer cells from spreading.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

Male pattern hair loss is genetic and influenced by hormones, with treatments like minoxidil and surgery available.

Korean and Caucasian men with male pattern baldness have different hair steroid levels.

Mutations in the Vitamin D receptor gene can cause hair loss similar to mutations in the Hairless gene.

Certain skin conditions can indicate insulin resistance and should prompt lifestyle changes and medical treatment to manage underlying health issues.

Most hirsutism patients had idiopathic hirsutism or PCOS, with hormonal imbalances and signs like acne and irregular periods.

Some nutrients and antioxidants may improve skin and hair health, but more research is needed to confirm these benefits.