Idiopathic Hypoparathyroidism with Extensive Intracranial Calcification in Children
April 2017
in “
Medicine
”
TLDR An 11-year-old boy in Saudi Arabia has a rare case of hypoparathyroidism with severe brain calcifications but normal development and no known cause.
This case report described an 11-year-old Saudi male with idiopathic hypoparathyroidism presenting with severe hypocalcemia and extensive intracranial calcifications beyond the basal ganglia (BG), a rare occurrence. Despite the extensive calcifications, the patient exhibited normal neurological function, intelligence, and development. Extensive testing ruled out known causes of hypoparathyroidism, including genetic mutations and autoimmune conditions. The patient responded well to calcium and vitamin D supplementation, maintaining stable calcium levels over a 5-year follow-up period. This was the first pediatric case reported from Saudi Arabia, highlighting the importance of thorough diagnostic exclusion in idiopathic hypoparathyroidism.
