research QR678 and QR678 Neo Hair Growth Formulations: A Cellular Toxicity and Animal Efficacy Study
QR 678 and QR 678 Neo are safe and promote hair growth, potentially helping chemotherapy-induced hair loss.
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research Quercetin and Polycystic Ovary Syndrome
Quercetin may help improve symptoms of polycystic ovary syndrome.
research The Need for Speed and Efficiency: A Brief Review of Small Molecule Antivirals for COVID-19
Some small molecule antivirals show promise against COVID-19, but more research is needed to understand and improve them.
research Highly Efficient Neural Differentiation of CD34-Positive Hair-Follicle-Associated Pluripotent Stem Cells Induced by Retinoic Acid and Serum-Free Medium
Hair follicle stem cells can become nerve cells using specific treatments.
research Trichoscopic Features of Male and Female Androgenetic Alopecia
The document concludes that signs of male and female pattern baldness include uneven hair thickness, yellow spots, skin discoloration around hair follicles, more thin and soft hairs, and many hair follicles with just one hair.
research A Kaleidoscope of Keratin Gene Expression and the Mosaic of Its Regulatory Mechanisms
Keratin protein production in cells is controlled by a complex system that changes with cell type, health, and conditions like injury or cancer.
research Effects of Bioactive Composition in Oryza Sativa L. Cv. KDML105 Bran Extract on Gene Expression Related to Hair Cycle in Human Hair Follicle Dermal Papilla Cells
KDML105 bran extract may help with hair growth and prevent hair loss.
research Updated Strategies for the Management, Pathogenesis, and Molecular Genetics of Different Forms of Ichthyosis Syndromes with Prominent Hair Abnormalities
Early diagnosis and tailored treatments are crucial for managing ichthyosis syndromes with hair abnormalities.
research Activation of TLR3 Enhances Stemness and Immunomodulatory Properties of Periodontal Ligament Stem Cells
Activating TLR3 improves the healing and immune properties of periodontal ligament stem cells.
research TRPV3 Ion Channel: From Gene to Pharmacology
The TRPV3 ion channel is important for skin and hair health and could be a target for treating skin conditions.
research The Men's Training Cup Keep Training: A Masturbation Aid Improves Intravaginal Ejaculatory Latency Time and Erection Hardness Score in Patients Unable to Delay Ejaculation
The Men's Training Cup Keep Training masturbation aid may help delay ejaculation and improve erectile function.
research Permanent Alopecia in Breast Cancer Patients: Role of Taxanes and Endocrine Therapies
Some breast cancer treatments, like taxanes, can cause long-term hair loss.
research Hair Thread Tourniquet Syndrome in a Male Infant: A Rare Surgical Emergency
A baby boy's toe was saved from damage caused by hair strangulation by quick surgical treatment.
research The Interplay of Oxidative Stress and Immune Dysfunction in Hashimoto’s Thyroiditis and Polycystic Ovary Syndrome: A Comprehensive Review
Oxidative stress and immune dysfunction are linked to both Hashimoto's thyroiditis and polycystic ovary syndrome, with diet and specific treatments important for managing these conditions.
research Alopecia Areata: Autoimmune Nature, Genetic Associations, and Treatments
Alopecia areata is an autoimmune disease with genetic links, treatable with certain medications, and can affect mental health.
research Androgenetic Alopecia: Pathogenetic Mechanisms and Treatment Approaches
Androgenic alopecia, a common hair loss condition, is linked to changes in androgen metabolism and genetics, and can be treated with finasteride and minoxidil, but these treatments are only fully effective in 10% of patients.
research Metabolic pathways of eicosanoids—derivatives of arachidonic acid and their significance in skin
This review examines the metabolic pathways of eicosanoids, derivatives of arachidonic acid, and their importance in skin health and disease. Eicosanoids, produced by skin cells, are vital for maintaining skin homeostasis and regulating inflammation. Dysregulation of these molecules can lead to skin conditions like psoriasis and atopic dermatitis. The document highlights the roles of enzymes such as cyclooxygenases, lipoxygenases, and cytochrome P450 in eicosanoid metabolism, affecting processes like keratinocyte differentiation and hair follicle development. It suggests that targeting these pathways could offer therapeutic benefits, particularly through COX-2 inhibitors and other pharmacological interventions. The review calls for further research to better understand eicosanoid roles in skin diseases and to develop effective diagnostic and therapeutic strategies.
research Genetics and Epigenetics of Polycystic Ovary Syndrome
Genes and epigenetic changes are important in the development of Polycystic Ovary Syndrome.
research Commonly Associated Disorders With Complete Scalp Alopecia in Early Childhood: A Review
Six genetic conditions are often linked to complete scalp hair loss in children.
research Maternal Androgen Excess Significantly Impairs Sexual Behavior in Male and Female Mouse Offspring: Perspective for a Biological Origin of Sexual Dysfunction in PCOS
Too much male hormone in mothers can negatively affect the sexual behavior of both male and female baby mice.
research Investigation of ROP GTPase Activity and Cytoskeleton Dynamics During Tip Growth in Root Hairs and Pollen Tubes
ROP GTPase helps control the growth of pollen tubes and root hairs by managing cell structure and movement.
research Hair Loss in an 11-Year-Old: Successful Treatment of Alopecia Universalis with Baricitinib and Minoxidil
An 11-year-old girl with severe hair loss was successfully treated with a new combination therapy.
research Laser on Hair Regrowth: Potential of Low-Level Laser Therapy
Low-Level Laser Therapy might be an effective alternative hair loss treatment for some people.
![Activity of 17β-(N-Alkyl/Arylformamido) and 17β-[(N-Alkyl/Aryl) Alkyl/Arylamido]-4-Methyl-4-Aza-5α-Androstan-3-Ones as 5α-Reductase Inhibitors in the Hamster Flank Organ and Ear](/images/research/861159f1-7bd4-420c-a16b-4829458efe68/small/15592.jpg)
research Activity of 17β-(N-Alkyl/Arylformamido) and 17β-[(N-Alkyl/Aryl) Alkyl/Arylamido]-4-Methyl-4-Aza-5α-Androstan-3-Ones as 5α-Reductase Inhibitors in the Hamster Flank Organ and Ear
The compounds tested could potentially treat hair loss and alopecia.
research Ketoconazole Therapy for Women with Acne and/or Hirsutism
Ketoconazole reduced hair growth and improved acne in women, but caused side effects needing careful monitoring.
research Effect of Finasteride on Adrenal Steroidogenesis in Men
Finasteride, when taken daily, lowers dihydrotestosterone levels but doesn't noticeably affect adrenal steroid production, except by blocking the 5 alpha-reductase enzyme.
research Possible Immunomodulating Effect of Retinol on Cytokine Secretion in Patients with Recurrent Furunculosis
Retinol may affect immune responses in people with frequent skin boils.
research New Progesterone Esters as 5α-Reductase Inhibitors
Some new progesterone derivatives are better at blocking testosterone conversion than a common drug.
research Activity of Sorafenib Against Desmoid Tumor/Deep Fibromatosis
Sorafenib is effective in treating Desmoid Tumor/Deep Fibromatosis.
research Association of Androgenetic Alopecia with Metabolic Syndrome: A Case-Control Study on 100 Patients in a Tertiary Care Hospital in South India
Androgenetic alopecia is significantly linked to metabolic syndrome.