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Different skin cells process testosterone differently, and certain drugs can change this process, possibly helping treat acne and hair loss.

17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.

Sebaceous glands play a key role in skin health, immunity, and various skin diseases.

A substance called compound-1 could help increase hair growth by maintaining prostaglandin levels in hair follicles.

DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.

The research found that polycystic ovary syndrome (PCOS) has two distinct types, with one having more severe hormone and insulin issues.

Hair lotions with 17 alpha-estradiol can reduce hair loss but won't regrow new hair.

17-β-Estradiol applied to the skin stops hair growth, while ICI 182 780 helps hair grow in mice.

Using 17-hydroxyprogesterone levels to diagnose nonclassic congenital adrenal hyperplasia can result in many incorrect diagnoses.

Measuring 17-hydroxyprogesterone in hair can help monitor androgen levels in people with congenital adrenal hyperplasia.

A young woman's symptoms suggested PCOS, but tests and surgery confirmed and treated a rare ovarian tumor, resolving her condition.

Spironolactone treatment reduced hair growth and androgen levels in hirsute women, but the overall effectiveness was just adequate.

Glioblastoma cells can make androgens, which might help the tumor grow.

Platelet-rich plasma (PRP) can help with hair loss and improve hair transplant results.

Transgender females can reach their target estrogen levels using estradiol patches, especially if oral treatments fail or if they're at risk for blood clots. Often, the highest dose patch is needed.

Tiny lipid particles carrying 17-α-estradiol gather in hair follicles, which may help target alopecia treatment.

Tiny lipid particles loaded with a hormone gather in hair follicles, which may help treat hair loss.

Metformin can start ovulation and may lower 17P response in PCOS, but six months is too short to improve hair growth or change body fat distribution.

A new antiandrogen compound was made and its detailed three-dimensional shape was described.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

IL-17 is a key target for treating inflammatory skin diseases, especially psoriasis.

An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.

Keratin 17 is linked to various diseases, including cancer and skin conditions, and may be a target for diagnosis and treatment.

People with alopecia areata have more Th17 cells and fewer Treg cells, which may be key to the condition's development.

Alopecia areata involves immune system imbalances that may lead to depression and anxiety.

Keratin 17 is modified by RSK1 in response to growth and stress, affecting skin growth and stress response.

AIRE protein, defective in APECED patients, is found in skin and hair cells and interacts with cytokeratin 17.