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Glossary Genomic Stability

ability of DNA to remain unchanged and accurately maintained

Genomic stability refers to the ability of an organism's genetic material (DNA) to remain unchanged and accurately maintained over time. This stability is crucial for normal cell function and preventing diseases like cancer, as it ensures that the genetic information is correctly passed on during cell division and not disrupted by mutations or structural alterations.

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Research

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research Generic Development of Topical Dermatologic Products: Formulation Development, Process Development, and Testing of Topical Dermatologic Products

188 citations , October 2012 in “The AAPS Journal”

This review discusses strategies for developing semi-solid topical generic products to match the quality of reference-listed drugs, using concepts like quality by design and reverse-engineering, but reports no new results.

research Gata6 promotes hair follicle progenitor cell renewal by genome maintenance during proliferation

29 citations , December 2016 in “The EMBO Journal”

This study found that the transcription factor Gata6 plays a crucial role in adult mouse hair follicle regeneration by promoting the renewal and preventing DNA damage of rapidly proliferating progenitor cells.

research Biomaterials Functionalized with MSC Secreted Extracellular Vesicles and Soluble Factors for Tissue Regeneration

220 citations , March 2020 in “Advanced functional materials”

This review discusses the mechanisms and potential therapeutic benefits of mesenchymal stromal cell-derived extracellular vesicles delivered via biomaterials, but reports no new clinical results.

research Biotin and biotinidase deficiency

166 citations , November 2008 in “Expert Review of Endocrinology & Metabolism”

This review discusses biotin and biotinidase deficiencies, their symptoms, and methods of medical management, without presenting new clinical findings.

research Progeroide Syndrome

2 citations , August 2023 in “Die Dermatologie”

This review discusses the molecular pathology of progeroid syndromes and reports no new results; the authors emphasize understanding these mechanisms to develop treatments and potentially improve quality of life for affected individuals.

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Community Join

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community No hair loss progress in 11 years. Why did my baldness stop?

21 upvotes 6 days ago

Hair loss can stop or slow down unpredictably, often due to genetic factors and hormone sensitivity. Some individuals experience early hairline changes that stabilize without treatment.

community If DHT is the cause of hair loss why do so many still lose hair on dutasteride?

in Finasteride/Dutasteride 9 upvotes 1 month ago

Hair loss can persist despite using treatments like finasteride, dutasteride, and minoxidil due to factors like genetic sensitivity, incomplete DHT blockage, and other hormonal influences. Individual responses vary, and some may require a combination of treatments to stabilize hair loss.

community No stabilisation after 12 months on Dut - is this it?

5 upvotes 1 month ago

The conversation discusses the lack of hair regrowth and continued thinning despite using dutasteride for 12 months after finasteride. Suggestions include increasing dutasteride dosage, considering oral minoxidil, addressing scalp health, and lifestyle changes.

community Propecia or Generic if I can get either for Free

in Finasteride/Dutasteride 3 upvotes 5 months ago

Finasteride and Propecia are essentially the same, but some people may respond differently due to inactive ingredients. If cost is not an issue, Propecia is preferred due to better quality control and consistent results.

community Rate my MPB Genetics: Can I run Primobolan/Masteron? (Detailed MyHeritage DNA Data Included)

in General 262 upvotes 6 months ago

The user is using testosterone and finasteride to prevent hair loss and is considering adding Primobolan or Masteron, which are DHT-derivatives. They are seeking advice on their genetic risk for male pattern baldness and whether they can safely use these compounds without significant hair loss.

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Learn

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learn Neem Oil

Oil from the neem tree, used in traditional remedies

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