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GlossaryGenomic Stability

ability of DNA to remain unchanged and accurately maintained

Genomic stability refers to the ability of an organism's genetic material (DNA) to remain unchanged and accurately maintained over time. This stability is crucial for normal cell function and preventing diseases like cancer, as it ensures that the genetic information is correctly passed on during cell division and not disrupted by mutations or structural alterations.

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community Minoxidil Sulfate makes everyone a responder

in Research/Science 249 upvotes 6 days ago

Minoxidil sulfate is more effective than regular minoxidil, especially for those with low sulfotransferase levels or scalp sensitivity, but it is unstable unless delivered in a liposomal format. Combining minoxidil with tretinoin can enhance effectiveness, and stopping minoxidil use can lead to rapid hair loss.

community Keratin microspheres - breakthrough

in Research/Science 13 upvotes 8 months ago

A gel of keratin microspheres promotes hair follicle growth, showing similar effectiveness to minoxidil in mice. The treatment activates hair growth pathways and reduces inflammation, with potential applications in drug delivery for hair-related disorders.

community after several weeks of research, here's the stack I've decided on

in Finasteride/Dutasteride 43 upvotes 3 months ago

A 23-year-old experiencing diffuse hair thinning has chosen a treatment stack including topical finasteride, a blend of rosemary, peppermint, and pumpkin seed oils, procyanidine B2 spray, ketoconazole shampoo, and scalp massages. They avoid minoxidil due to family history of side effects and oral finasteride due to high estrogen levels.

community 3.5 months progress on only oral finasteride 1.25mg daily

in Update 455 upvotes 3 months ago

User shared 3.5 months progress on oral finasteride 1.25mg daily with no side effects. Other users commented on the effectiveness and shared their experiences.

community DIY treatment... Shedding completely stopped after 1.5 yrs

in Treatment 249 upvotes 2 years ago

Vitamin C mixed with shampoo stopped shedding and promoted hair regrowth after 1.5 years. Both the person and their wife experienced significant hair loss reduction with this method.

community Why balding gets worse in every generation?

in Chat 81 upvotes 4 months ago

Balding seems to worsen with each generation, possibly due to stress, diet, and environmental factors. The user started treatments like Minoxidil and finasteride.

community Boys I am just a gonner. What on earth is my scalp even going through. Looks like world war 3. Pyril 3 months. Topical melitonin/progesterone/fin, dut, fin, oral min, laser trash, anus stimulation. Nothing. Donor area is decimated 😂.

in Progress Pictures 83 upvotes 2 years ago

Treating Seborrheic Dermatitis, a fungal scalp condition which can cause hair loss. Treatments discussed include antifungal shampoos, cold showers, exfoliating the scalp, taking Vitamin D, and stimulating the prostate through the anus.

community maybe some of you need to hear this

in Chat 326 upvotes 2 years ago

Coping with hair loss, the effects of finasteride and minoxidil, and strategies for maintaining self-esteem while experiencing hair loss.

community Hey guys I’m a Compounding Pharmacist specialized in Hair-loss who makes Topical Finasteride Foam +/- minoxidil

in Treatment 28 upvotes 3 years ago

A compounding pharmacist offers affordable topical finasteride foam with Anagain and micro-dose finasteride capsules for hair loss. They provide telehealth services across Canada and private appointments for international patients.

community Fin user for almost 5 years giving my positive experience and advices

in Finasteride/Dutasteride 94 upvotes 6 months ago

A user shared a positive 5-year experience with oral finasteride and minoxidil for hair loss, noting improvement and stability. Others in the conversation also reported positive results with these treatments.

community 1 Year on just Fin 1mg 3 times/week

in Progress Pictures 838 upvotes 4 months ago

A user shared their one-year progress using finasteride 1mg three times a week, starting at age 25, with noticeable regrowth after three months and no side effects. Other users discussed their experiences with finasteride, minoxidil, microneedling, and dutasteride, noting varying results and side effects.

community The Importance of Not Rushing Your Treatment Protocol

in Treatment 10 upvotes 2 years ago

Taking a slow and steady approach to treating hair loss, as well as the potential risks of combining too many treatments. The post suggests trialling individual treatments (such as Minoxidil, finasteride, or RU58841) for an extended period before adding more into your treatment protocol.

community Finasteride saved my life, 1.5y in (23M)

in Progress Pictures 1176 upvotes 1 year ago

The conclusion of the conversation is that some users have had positive results with finasteride for hair loss, while others have not. The effectiveness of finasteride varies from person to person.

community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

in Research/Science 739 upvotes 2 years ago

A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

community Loosing ground, on fin and min. 4years progression

in Update 191 upvotes 1 month ago

The user has been using finasteride and minoxidil for hair loss since 2021, with some initial regrowth but now considering switching to dutasteride due to concerns about further hair loss. They also use microneedling and are exploring tretinoin, while others suggest adding oral minoxidil or a hair transplant for better results.

community M19, Progress pics, fin monotherapy. 1 month vs 5 months

in Progress Pictures 175 upvotes 4 months ago

A user shared progress pictures after 5 months of using finasteride, noting hair growth and minimal side effects. They suggested adding minoxidil for further hair growth if needed.

community 2 years and (almost) 2 months on finasteride, dermarolling and minoxidil. 3 months on Dutasteride 0.5 mg.

in Progress Pictures 198 upvotes 1 year ago

The user shared their successful hair loss treatment journey over two years using finasteride, dermarolling, minoxidil, and dutasteride. They discussed their regimen, showed progress pictures, and answered questions about their experience, inspiring others with similar issues.

community I’m gutted and this is my last post on this thread

in Update 190 upvotes 2 years ago

User tried various hair loss treatments without success and plans to consult a dermatologist and possibly shave head for emotional well-being.

community 2 months topical dutasteride plus minoxidil, very happy with the results!

in Finasteride/Dutasteride 339 upvotes 3 years ago

A user's success in treating their hair loss with 2x daily topical dutasteride and minoxidil, as well as the potential for using less frequent application of topical dutasteride due to its long half-life.

community When you're balding is it an absolute traumatic period of your life or do some people not care as much?

in Chat 89 upvotes 3 months ago

Balding can be traumatic for many, affecting self-esteem and social interactions, while others accept it more easily. Treatments mentioned include finasteride, minoxidil, and RU58841.

community My journey from Norwood 3.5/4 to Norwood 0

in Transplants 251 upvotes 8 months ago

A user's hair regrowth journey involved a hair transplant and using RU58841, finasteride, and minoxidil, with side effects managed by other medications.

community Anyone else growing tired of the finasteride wars?

in Finasteride/Dutasteride 169 upvotes 1 year ago

The conversation is about differing experiences with finasteride for hair loss, with some users reporting side effects and others not, and the debate over the drug's safety and effectiveness. Specific treatments mentioned include finasteride, dutasteride, and topical finasteride.

community Is DUT better or worse than FIN?

in Finasteride/Dutasteride 62 upvotes 1 year ago

The conversation discusses the effectiveness of Dutasteride (DUT) and Finasteride (FIN) for hair loss. Users share varied experiences, with some finding DUT more effective and others experiencing side effects or no change, highlighting that individual responses can vary.

community Dutasteride 2 years 3 month results

in Finasteride/Dutasteride 251 upvotes 1 year ago

The user tried dutasteride for hair loss for 2.5 years but experienced drastic thinning and receding hairline. They decided to switch back to finasteride, along with minoxidil, LLLT, and ketoconazole, due to dissatisfaction with dutasteride's results and side effects.

community Considering adding oral min. I’ve been on fin for 8 years. First picture is from when I was 20, second 30. The rest are now. I’m 32

in Progress Pictures 1122 upvotes 1 year ago

The user "PowerfulAide6677" shared progress pictures of their hair loss journey, mentioning that they have been on finasteride for 8 years and are considering adding oral minoxidil to fill in their hairline. Some users advised against adding oral minoxidil, suggesting that the user's current maintenance with finasteride is sufficient.

community Why I believe PFS is not a "real" condition (and what I believe it is instead)

in Finasteride/Dutasteride 14 upvotes 1 year ago

The post argues that Post-Finasteride Syndrome (PFS) is likely not real and suggests symptoms may be due to mental health issues or the nocebo effect. The conversation includes personal experiences with finasteride, highlighting both positive and negative effects, and emphasizes consulting doctors and using reliable sources for medication.

community Hairline recovery after severe hair loss

in Progress Pictures 88 upvotes 2 years ago

A user's hairline recovery after severe hair loss, which was treated with Dutasteride and Minoxidil; other users offered their opinions on the severity of the hair loss.

community Father trying to save his 17 year old son from MPB

in Progress Pictures 160 upvotes 2 years ago

Father assists son with hair loss using Finasteride Propecia. Son's hair improves, considers adding Minoxidil or Dutasteride for better results.

community No side effects on pyrilutamide / KX-826 so far

in Research/Science 207 upvotes 3 years ago

User TopBack56 and friends tried pyrilutamide (KX-826) for hair loss without experiencing negative side effects. They observed fine vellus hairs but no thick hair growth yet, and plan to add GT20029 to their regime after safety trials.

community I've been afraid to start Finasteride treatment for 5 years, on it for 2 weeks, regret that hadn't started it earlier and here's my story

in Finasteride/Dutasteride 31 upvotes 3 years ago

A 28-year-old male, losing hair since his teens, started taking 0.31 mg finasteride daily for two weeks with no side effects and regrets not starting earlier. He tried various treatments like minoxidil, scalp massages, and vitamins but found finasteride most effective.