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GlossaryGenomic Regions

specific DNA segments with distinct functions or characteristics

Genomic regions are specific segments of DNA within an organism's genome that have distinct functions or characteristics. These regions can include genes, which code for proteins, as well as regulatory elements that control gene expression, and non-coding areas that may have structural or other roles. Understanding these regions helps scientists identify how genetic variations can influence traits and diseases, such as alopecia.

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Taking Advantage of Phenotype Variability in a Local Animal Genetic Resource: Identification of Genomic Regions Associated with the Hairless Phenotype in Casertana Pigs

research Taking Advantage of Phenotype Variability in a Local Animal Genetic Resource: Identification of Genomic Regions Associated with the Hairless Phenotype in Casertana Pigs

16 citations, April 2018 in “Animal Genetics”

Researchers found two genes that may explain why some Casertana pigs don't have hair.

Genome Wide Association Analysis of Root Hair Traits in Rice Reveals Novel Genomic Regions Controlling Epidermal Cell Differentiation

research Genome Wide Association Analysis of Root Hair Traits in Rice Reveals Novel Genomic Regions Controlling Epidermal Cell Differentiation

2 citations, January 2023 in “BMC plant biology”

Scientists found new genetic areas that affect how rice root hairs grow and develop.

research Haplotypes Spanning Centromeric Regions Reveal Persistence of Large Blocks of Archaic DNA

49 citations, June 2019 in “eLife”

Ancient DNA blocks are still present in human genomes, possibly due to advantages they provide.

research Selection Signatures for Fiber Production in Commercial Species: A Review

5 citations, November 2022 in “Animal Genetics”

Genomic research can help improve the quality and production of natural fibers in animals.

research Hunting the Genes in Male-Pattern Alopecia: How Important Are They, How Close Are We and What Will They Tell Us?

46 citations, February 2016 in “Experimental Dermatology”

Genes play a significant role in male-pattern baldness, and understanding them could lead to new treatments and insights into related health issues.

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community M18 Is it smart to start with minox only?

in General 124 upvotes 2 weeks ago

An 18-year-old is considering starting minoxidil for hair loss due to a receding hairline but is hesitant about using finasteride due to age and lack of health insurance. A suggestion was made to use topical finasteride and minoxidil, along with lifestyle changes like exercise and cold showers.

community We Need A Solution For The Inflammatory Response related To AGA

in Research/Science 16 upvotes 3 months ago

The conversation is about finding a solution for scalp inflammation related to AGA, with the user expressing frustration that Minoxidil and Finasteride do not address inflammation. The user has researched glucocorticoids and topical NSAIDs for reducing inflammation and seeks advice from specialists.

community How is it possible for someone to be a non responder to ORAL minoxidil?

in Minoxidil 66 upvotes 8 months ago

Some individuals do not respond to oral minoxidil for hair loss, despite it generally working by improving blood flow to hair follicles. Factors like metabolism, drug interactions, and individual variations in the drug's activation may influence its effectiveness.

community Protac degradation of the androgen receptor in mice shows good efficacy and no systemic drug could be found

in Research/Science 47 upvotes 1 year ago

The efficacy of degrading the androgen receptor through dermal application in DP cells, a delivery system for topical drugs that involves dissolving microneedles, and rosemary oil as an alternative anti-androgen.

community Evidenced Based Meta-Analyses and Systemic Reviews of Androgenic Alopecia and Treatments

in Research/Science 14 upvotes 4 years ago

Evidence-based treatments for androgenic alopecia, such as minoxidil, finasteride, low-level laser light therapy, dutasteride, platelet-rich plasma, and topical ketoconazole. It discusses the efficacy, safety, and mechanism of action of these treatments, as well as future developments in understanding this polygenic condition.

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