Defolliculated (Dfl): A Dominant Mouse Mutation Leading to Poor Sebaceous Gland Differentiation and Total Elimination of Pelage Follicles

    July 2002 in “ Journal of Investigative Dermatology ”
    Rebecca M. Porter, Declan P. Lunny, G.M. Henderson … Thomas M. Magin
    Studysummary The Dfl mutation in mice causes poor sebaceous gland function and complete hair loss.
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    Research cited in this study 11

    1. Tcf3 and Lef1 Regulate Lineage Differentiation of Multipotent Stem Cells in Skin Genes & Development · 2001
    2. A Unique Type I Keratin Intermediate Filament Gene Family Is Abundantly Expressed in the Inner Root Sheaths of Sheep and Human Hair Follicles Journal of Investigative Dermatology · 2001
    3. Morphogenesis and Renewal of Hair Follicles from Adult Multipotent Stem Cells Cell · 2001
    4. Asebia-2J (Scd1ab2J): A New Allele and a Model for Scarring Alopecia ˜The œAmerican journal of pathology · 2000
    5. The Biology of Hair Follicles The New England Journal of Medicine · 1999
    6. Hair Follicle Biology, the Sebaceous Gland, and Scarring Alopecias Archives of dermatology · 1999
    7. Molecular and Functional Aspects of the Hairless (Hr) Gene in Laboratory Rodents and Humans Experimental Dermatology · 1998
    8. Genetically Null Mice Reveal a Central Role for Epidermal Growth Factor Receptor in the Differentiation of the Hair Follicle and Normal Hair Development PubMed · 1997
    9. Expression of a Dominant Negative Mutant of Epidermal Growth Factor Receptor in the Epidermis of Transgenic Mice Elicits Striking Alterations in Hair Follicle Development and Skin Structure. The EMBO Journal · 1995
    10. Handbook of Mouse Mutations with Skin and Hair Abnormalities: Animal Models and Biomedical Tools Medical Entomology and Zoology · 1994
    11. The Secret Life of the Hair Follicle Trends in genetics · 1992

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