Transcriptome And Proteome Combined Analysis Of Wool Fiber Diameter Regulation Mechanism

    September 2025 in “ Animal Bioscience ”
    Lin Yue, Zengkui Lu, Tingting Guo … Chao Yuan
    Studysummary This study found that triglyceride and energy metabolic pathways are crucial factors influencing wool fiber diameter in fine-wool Alpine Merino sheep, providing insights for enhancing wool quality.
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    Research cited in this study 14

    1. Transcriptome Meta-Analysis Reveals Genetic Rules in Six Animal Breeds and Genes Associated with Wool Fineness Frontiers in Genetics · 2024
    2. MiR-23b and miR-133 Co-Target TGFβ2/NOTCH1 in Sheep Dermal Fibroblasts, Affecting Hair Follicle Development Cells · 2024
    3. Integration Analysis of Hair Follicle Transcriptome and Proteome Reveals the Mechanisms Regulating Wool Fiber Diameter in Angora Rabbits International journal of molecular sciences · 2024
    4. Hair Follicle Morphogenesis During Embryogenesis, Neogenesis, and Organogenesis Frontiers in Cell and Developmental Biology · 2022
    5. Gene Network Analysis Reveals Candidate Genes Related to Hair Follicle Development in Sheep BMC genomics · 2022
    6. The Fiber Diameter Traits of Tibetan Cashmere Goats Are Governed by the Inherent Differences in Stress, Hypoxic, and Metabolic Adaptations: An Integrative Study of Proteome and Transcriptome BMC Genomics · 2022
    7. Wnt/β-Catenin Signaling: Function, Biological Mechanisms, and Therapeutic Opportunities Signal Transduction and Targeted Therapy · 2022
    8. Human Hair Follicles Operate an Internal Cori Cycle and Modulate Their Growth via Glycogen Phosphorylase Scientific Reports · 2021
    9. Comprehensive Transcriptome and Methylome Analysis Delineates the Biological Basis of Hair Follicle Development and Wool-Related Traits in Merino Sheep BMC Biology · 2021
    10. Discovery of Genes and Proteins Possibly Regulating Mean Wool Fibre Diameter Using cDNA Microarray and Proteomic Approaches Scientific reports · 2020
    11. Dermal Fibroblasts in Cutaneous Development and Healing Wiley Interdisciplinary Reviews-Developmental Biology · 2017
    12. A Comparison of Transcriptomic Patterns Measured in the Skin of Chinese Fine and Coarse Wool Sheep Breeds Scientific reports · 2017
    13. Integrated Analysis of Coding Genes and Non-Coding RNAs During Hair Follicle Cycle of Cashmere Goat (Capra Hircus) BMC Genomics · 2017
    14. Cell Movement in the Hair Follicle Dermis: More Than a Two-Way Street? Journal of Investigative Dermatology · 2003