The Safety and Efficacy of a Proprietary Bioactive Fatty Acids Extract From Saw Palmetto (Serenoa Repens) for Promoting Hair Growth and Reducing Hair Loss in Adults With Self-Perceived Thinning Hair: 90-Day Results

    November 2025 in “ Journal of Cosmetic Dermatology ”
    Glynis Ablon, Glynis Ablon
    Studysummary This study found that a proprietary saw palmetto (Serenoa repens) extract significantly increased hair growth and reduced hair shedding in men and women with self-perceived thinning hair over a 90-day period, compared to placebo, without reported adverse events.
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    Research cited in this study 15

    1. Male And Female Pattern Hair Loss Australian Prescriber · 2025
    2. Comprehensive Evaluation of Androgenetic Alopecia: Demographic Characteristics, Psychosocial Impact, and the Role of Social Media in Treatment Choices Journal of Cosmetic Dermatology · 2025
    3. Multidimensional Assessment of Adverse Events of Finasteride: A Real-World Pharmacovigilance Analysis Based on FDA Adverse Event Reporting System (FAERS) from 2004 to April 2024 PLoS ONE · 2025
    4. Types and Characteristics of Hair Across the Globe: Results of a Multinational Study on 19,461 Individuals Clinical Cosmetic and Investigational Dermatology · 2025
    5. Androgenetic Alopecia: An Update JAAD International · 2023
    6. Lipid Profile and 5α-Reductase Inhibition Activity of Proprietary Ultrahigh-Pressure Supercritical Carbon Dioxide and Hexane Saw Palmetto Extracts Uro · 2023
    7. Common Causes of Hair Loss: Clinical Manifestations, Trichoscopy, and Therapy Journal of the European Academy of Dermatology and Venereology · 2020
    8. A Review of the Treatment of Male Pattern Hair Loss Expert Opinion on Pharmacotherapy · 2020
    9. Natural Hair Supplement: Friend or Foe? Saw Palmetto, A Systematic Review in Alopecia Skin appendage disorders · 2020
    10. Treatment of Male Androgenetic Alopecia with Topical Products Containing Serenoa Repens Extract Australasian Journal of Dermatology · 2015
    11. Comparative Effectiveness of Finasteride vs Serenoa Repens in Male Androgenetic Alopecia: A Two-Year Study International Journal of Immunopathology and Pharmacology · 2012
    12. Prevalence of Male and Female Pattern Hair Loss in Maryborough Journal of Investigative Dermatology Symposium Proceedings · 2005
    13. EEMCO Guidance for the Assessment of Hair Shedding and Alopecia Skin Pharmacology and Physiology · 2004
    14. Hypertrichosis in Females Applying Minoxidil Topical Solution and in Normal Controls Journal of The European Academy of Dermatology and Venereology · 2003
    15. A Randomized, Double-Blind, Placebo-Controlled Trial to Determine the Effectiveness of Botanically Derived Inhibitors of 5-Alpha-Reductase in the Treatment of Androgenetic Alopecia Journal of Alternative and Complementary Medicine · 2002