Isolation, Expansion, And Characterization Of Rat Hair Follicle Stem Cells And Their Secretome: Insights Into Wound Healing Potential

    December 2024 in “ Biomedicines ”
    Patrícia Sousa, Bruna Lopes, Ana Catarina Sousa … Ana Colette Maurício
    Studysummary In this study, researchers developed methods to isolate and culture rat hair follicle stem cells, confirming their potential for skin regeneration by analyzing growth characteristics and bioactive secretions, contributing to regenerative medicine advancements.
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    Research cited in this study 19

    1. Applications of Mesenchymal Stem Cells in Skin Regeneration and Rejuvenation International Journal of Molecular Sciences · 2021
    2. Epidermal Stem Cells in Hair Follicle Cycling and Skin Regeneration: A View From the Perspective of Inflammation Frontiers in Cell and Developmental Biology · 2020
    3. Tp63-Expressing Adult Epithelial Stem Cells Cross Lineage Boundaries Revealing Latent Hairy Skin Competence Nature Communications · 2020
    4. Hair-Bearing Human Skin Generated Entirely From Pluripotent Stem Cells Nature · 2020
    5. Locally Delivered Umbilical Cord Mesenchymal Stromal Cells Reduce Chronic Inflammation in Long-Term Nonhealing Wounds: A Randomized Study Stem Cells International · 2020
    6. Hair Follicle Stem Cells Differentiation Into Bone Cells on Collagen Scaffold Cell and Tissue Banking · 2020
    7. Epidermal Stem Cells in Wound Healing and Regeneration Stem Cells International · 2020
    8. Skin Stem Cells, Their Niche, and Tissue Engineering Approach for Skin Regeneration Advances in experimental medicine and biology · 2019
    9. Mesenchymal Stem Cell Secretome: Toward Cell-Free Therapeutic Strategies in Regenerative Medicine International Journal of Molecular Sciences · 2017
    10. Stem Cells Applications In Regenerative Medicine And Disease Therapeutics International Journal of Cell Biology · 2016
    11. Stem Cells in Skin Regeneration, Wound Healing, and Their Clinical Applications International journal of molecular sciences · 2015
    12. Culture and Characterization of Rat Hair Follicle Stem Cells Cytotechnology · 2014
    13. Stem Cell Dynamics in the Hair Follicle Niche Seminars in Cell & Developmental Biology · 2013
    14. Structure and Function of Skin, Hair, and Nails Medicine · 2009
    15. Comparative Characterization of Hair Follicle Dermal Stem Cells and Bone Marrow Mesenchymal Stem Cells Stem Cells and Development · 2006
    16. Bulge Cells of Human Hair Follicles: Segregation, Cultivation, and Properties Colloids and Surfaces B: Biointerfaces · 2006
    17. Characterization and Isolation of Stem Cell-Enriched Human Hair Follicle Bulge Cells ˜The œJournal of clinical investigation/˜The œjournal of clinical investigation · 2005
    18. Multipotent Nestin-Positive, Keratin-Negative Hair-Follicle Bulge Stem Cells Can Form Neurons Proceedings of the National Academy of Sciences · 2005
    19. Hair Follicle Dermal Cells Differentiate Into Adipogenic and Osteogenic Lineages Experimental Dermatology · 2003

    Related research 3

    1. Tissue Engineered Human Hair Follicles from Genetically, Environmentally, and Extrinsically Reprogrammed Dermal Papilla Cells ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2017
    2. Keratins of the Human Hair Follicle International review of cytology · 2005
    3. Trans-Species Hair Growth Induction by Human Hair Follicle Dermal Papillae Experimental Dermatology · 2001