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    Sequential Scalp Assessment in Hair Regeneration Therapy Using an Adipose-Derived Stem Cell-Conditioned Medium

    September 2019 in “ Dermatologic Surgery ”
    Keigo Narita, Hirotaro Fukuoka, Takuya Sekiyama … Kiyonori Harii
    Studysummary This study found that intradermal administration of adipose-derived stem cell–conditioned medium significantly increased hair density and dermal thickness, suggesting potential regenerative effects on both hair follicles and the interfollicular scalp in patients with alopecia.
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    Research cited in this study 13

    1. Hair Regeneration Therapy: Application of Adipose-Derived Stem Cells Current stem cell research & therapy · 2017
    2. Clinical Use of Conditioned Media of Adipose Tissue-Derived Stem Cells in Female Pattern Hair Loss: A Retrospective Case Series Study International Journal of Dermatology · 2015
    3. The Latest Advance in Hair Regeneration Therapy Using Proteins Secreted by Adipose-Derived Stem Cells The American Journal of Cosmetic Surgery · 2012
    4. Adipocyte Lineage Cells Contribute to the Skin Stem Cell Niche to Drive Hair Cycling Cell · 2011
    5. Hair Growth Stimulated by Conditioned Medium of Adipose-Derived Stem Cells Is Enhanced by Hypoxia: Evidence of Increased Growth Factor Secretion Biomedical research · 2010
    6. Hair Growth Promoting Effects of Adipose Tissue-Derived Stem Cells Journal of Dermatological Science · 2009
    7. PDGF Isoforms Induce and Maintain Anagen Phase of Murine Hair Follicles Journal of Dermatological Science · 2006
    8. Sgk3 Links Growth Factor Signaling to Maintenance of Progenitor Cells in the Hair Follicle The Journal of Cell Biology · 2005
    9. Control of Hair Growth and Follicle Size by VEGF-Mediated Angiogenesis Journal of Clinical Investigation · 2001
    10. Functional Analysis of the Stratum Corneum of Scalp Skin: Studies in Patients with Alopecia Areata and Androgenetic Alopecia Archives of Dermatological Research · 2000
    11. Insulin-Like Growth Factor 1 and Hair Growth Dermatology Online Journal · 1999
    12. Local Injection of Hepatocyte Growth Factor/Scatter Factor Alters Cyclic Growth of Murine Hair Follicles Journal of Investigative Dermatology · 1998
    13. Classification of the Types of Androgenetic Alopecia (Common Baldness) Occurring in the Female Sex British Journal of Dermatology · 1977

    Related research 7

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    2. Safety and Efficacy of Trimax-360 Serum in Healthy Adult Subjects with Mild to Moderate Alopecia of the Scalp Journal of Cosmetic Dermatology · 2022
    3. Significant Relationship Between Temporal Hair Loss and Other Scalp Areas in Female Pattern Hair Loss Journal of Dermatology · 2020
    4. Protection Against Chemotherapy-Induced Alopecia: Targeting ATP-Binding Cassette Transporters in the Hair Follicle Trends in pharmacological sciences · 2013
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    6. The Changing Patterns of Hair Density and Thickness in South Korean Women with Hair Loss: Clinical Office-Based Phototrichogram Analysis International Journal of Dermatology · 2008
    7. Towards a Molecular Understanding of Hair Loss and Its Treatment Trends in Molecular Medicine · 2001