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    Post-Finasteride Syndrome: A Review of Current Literature

    July 2018 in “ Current Sexual Health Reports
    Jeffrey K. Than, Katherine M. Rodriguez, Mohit Khera
    Studysummary This review discusses the occurrence of persistent sexual, physical, neurological, and psychiatric side effects known as post-finasteride syndrome after 5x-reductase inhibitor treatment, and emphasizes the importance of evaluating these risks for patients with benign prostatic hyperplasia or androgenic alopecia.
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    Research cited in this study 20

    1. Post-Finasteride Syndrome: What to Tell Our Female Patients? British Journal of Dermatology · 2018
    2. Research Brief: Self-Reports of Persistent Antiandrogenic, Estrogenic, Physical, and Psychological Effects of Finasteride Usage Among Men American Journal of Men's Health · 2018
    3. Neuroactive Steroid Levels and Psychiatric and Andrological Features in Post-Finasteride Patients The Journal of Steroid Biochemistry and Molecular Biology · 2017
    4. Persistent Erectile Dysfunction in Men Exposed to 5α-Reductase Inhibitors, Finasteride, or Dutasteride PeerJ · 2017
    5. Safety Profile of Finasteride: Distribution of Adverse Effects According to Structural and Informational Dichotomies of the Mind/Brain Clinical Drug Investigation · 2017
    6. Post-Finasteride Adverse Effects in Male Androgenic Alopecia: A Case Report of Vitiligo Skin Pharmacology and Physiology · 2017
    7. Androgen Receptor (AR) Gene (CAG)n and (GGN)n Length Polymorphisms and Symptoms in Young Males With Long-Lasting Adverse Effects After Finasteride Use Against Androgenic Alopecia Sexual Medicine · 2016
    8. Finasteride in Androgenic Alopecia Journal of the Dermatology Nurses’ Association · 2016
    9. Characteristics of Men Who Report Persistent Sexual Symptoms After Finasteride Use for Hair Loss The Journal of Clinical Endocrinology and Metabolism · 2016
    10. Effect of 5α-Reductase Inhibitors on Sexual Function: A Meta-Analysis and Systematic Review of Randomized Controlled Trials The Journal of Sexual Medicine · 2016
    11. Atypical Post-Finasteride Syndrome: A Pharmacological Riddle Indian Journal of Pharmacology · 2016
    12. Emotional Consequences of Finasteride: Fool’s Gold American Journal of Men's Health · 2016
    13. An Observational Retrospective Evaluation of 79 Young Men with Long-Term Adverse Effects After Use of Finasteride Against Androgenetic Alopecia International Journal of Andrology · 2016
    14. Finasteride, Not Tamsulosin, Increases Severity of Erectile Dysfunction and Decreases Testosterone Levels in Men With Benign Prostatic Hyperplasia Hormone Molecular Biology and Clinical Investigation · 2015
    15. Immunohistochemical Evaluation of Androgen Receptor and Nerve Structure Density in Human Prepuce from Patients with Persistent Sexual Side Effects after Finasteride Use for Androgenetic Alopecia PLOS ONE · 2014
    16. Persistent Sexual, Emotional, and Cognitive Impairment Post-Finasteride American Journal of Men's Health · 2014
    17. Persistent Sexual Side Effects of Finasteride: Could They Be Permanent? The Journal of Sexual Medicine · 2012
    18. Adverse Side Effects of 5α-Reductase Inhibitors Therapy: Persistent Diminished Libido, Erectile Dysfunction, and Depression in a Subset of Patients The Journal of Sexual Medicine · 2010
    19. Finasteride 5mg and Sexual Side Effects: How Many Are Related to a Nocebo Phenomenon? The Journal of Sexual Medicine · 2007
    20. Marked Suppression of Dihydrotestosterone in Men with Benign Prostatic Hyperplasia by Dutasteride, a Dual 5α-Reductase Inhibitor ˜The œJournal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism · 2004

    Related research 8

    1. Finasteride and Androgenic Alopecia: From Therapeutic Options to Medical Implications Journal of Dermatological Treatment · 2019
    2. Post-Finasteride Syndrome: A Review of Current Literature Current Sexual Health Reports · 2018
    3. The Post-Finasteride Syndrome: An Overview Journal of Mind and Medical Sciences · 2016
    4. Finasteride Side Effects and Post-Finasteride Syndrome in Male Androgenic Alopecia Journal of Mind and Medical Sciences · 2015
    5. Oral Finasteride Presents With Sexual-Unrelated Withdrawal in Long-Term Treated Androgenic Alopecia in Men PubMed · 2015
    6. 5α-Reductase Inhibitors in Androgenetic Alopecia Current Opinion in Endocrinology, Diabetes and Obesity · 2014
    7. Adverse Side Effects of 5α-Reductase Inhibitors Therapy: Persistent Diminished Libido, Erectile Dysfunction, and Depression in a Subset of Patients The Journal of Sexual Medicine · 2010
    8. Effect of Finasteride, a 5 Alpha-Reductase Inhibitor, on Serum Gonadotropins in Normal Men The Journal of Clinical Endocrinology and Metabolism · 1992