Post-Finasteride Syndrome: A Review of Current Literature

    July 2018 in “ Current Sexual Health Reports ”
    Jeffrey K. Than, Katherine M. Rodriguez, Mohit Khera
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    TLDR Post-finasteride Syndrome causes lasting negative effects, but more research is needed for treatment and risk evaluation.
    This document is a review of current literature on Post-finasteride Syndrome (PFS), a condition where men experience persistent adverse sexual, physical, neurological, and psychiatric effects after taking 5α-reductase inhibitors for benign prostatic hyperplasia (BPH) or androgenetic alopecia (AGA). The review highlights the lack of randomized clinical trials and treatment options for PFS, as well as the potential selection and recall bias in studies that rely on patient surveys and online forums. However, the existing evidence supports an association between 5α-reductase inhibitor use and PFS symptoms. The authors suggest that further research is needed to better evaluate the risks and benefits of using these agents for patients with BPH and AGA while exploring methods to ameliorate the adverse effects.
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      community EU Shouldn't Ban Fin & Dut: PFS is NOT REAL.

      in Research/Science  12 upvotes 7 months ago
      Finasteride and Dutasteride do not cause depression or "Post Finasteride Syndrome," with concerns often linked to the nocebo effect and preexisting mental health issues. The EU is unlikely to ban these drugs, but access may become more restricted due to ongoing debates.

      community 1 month of using fin, so happy

      in Progress Pictures  869 upvotes 11 months ago
      User had a hair transplant and used a finasteride and minoxidil spray for 6 months with no results. After adding finasteride tablets for 1 month, they saw significant hair growth improvement.

      community Another clueless guy fearmongering and spreading misinformation

      in Chat  251 upvotes 1 year ago
      The conversation discusses hair loss treatments, with some users advocating for finasteride and minoxidil, while others express concerns about potential side effects of finasteride. A social media influencer is criticized for promoting scalp massages and minoxidil over finasteride, which some believe is misinformation.

      community risks with finasteride and dutasteride

      in Research/Science  140 upvotes 2 weeks ago
      Finasteride and dutasteride have potential risks, including post-finasteride syndrome, but are commonly used for hair loss. RU58841, minoxidil, and needling are suggested as alternatives, though all treatments carry risks.

      community NW5 at 19. How many grafts do I need?

      in Transplants  139 upvotes 1 year ago
      A 19-year-old with rapid hair loss since 16 is considering a hair transplant but refuses to take finasteride or any 5α-Reductase inhibitors. They are currently using minoxidil, tretinoin, and microneedling with a Derminator 2, and only want hair until age 27.

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