5-Bromo-2′-Deoxyuridine Induced Effluvium via p53-Mediated CD326-Positive Keratinocyte Apoptosis in C57BL/6 Mice

    August 2016 in “ Journal of Dermatology ”
    Kyungjun Uh, Wu Jeong Hwang, Ji-Hyun Bae … Su-Cheong Yeom
    Studysummary This research successfully established a novel mouse model for anagen effluvium using BrdU treatment, which induced hair loss and pathological changes mimicking human symptoms.
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    Research cited in this study 11

    1. Pregnancy in Postpartum Estrus Induces Inflammatory Milk Production and Catagen-Specific Pup Skin Inflammation in Interleukin-10 Deficient Mice Journal of Dermatological Science · 2013
    2. Anagen Effluvium: A Review of Rapid Hair Loss During Growth Phase and Loose Anagen Hair Syndrome Indian Journal of Dermatology, Venereology and Leprology · 2013
    3. Maternal PPARγ Protects Nursing Neonates by Suppressing the Production of Inflammatory Milk Genes & Development · 2007
    4. Drug Reactions Affecting Hair: Diagnosis Dermatologic Clinics · 2007
    5. Prevalence of Male and Female Pattern Hair Loss in Maryborough Journal of Investigative Dermatology Symposium Proceedings · 2005
    6. A Guide to Assessing Damage Response Pathways of the Hair Follicle: Lessons From Cyclophosphamide-Induced Alopecia in Mice Journal of Investigative Dermatology · 2005
    7. Androgenetic Alopecia in Men Aged 40-69 Years: Prevalence and Risk Factors British Journal of Dermatology · 2003
    8. Protection Against Cytosine Arabinoside-Induced Alopecia by Minoxidil in a Rat Animal Model International Journal of Dermatology · 1995
    9. Drug-Induced Hair Loss and Hair Growth Drug Safety · 1994
    10. Chemotherapy-Induced Alopecia Southern Medical Journal · 1993
    11. Treatment with ImuVert and N-Acetylcysteine Protects Rats from Cyclophosphamide and Cytarabine-Induced Alopecia Cancer investigation · 1992

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