Mutant Laboratory Mice With Abnormalities in Hair Follicle Morphogenesis, Cycling, and Structure: Annotated Tables

December 2001 in “ Experimental dermatology ”

Motonobu Nakamura, John P. Sundberg, Ralf Paus

hair follicle morphogenesis hair follicle cycling hair follicle structure sebaceous gland structure hair growth disorders genetic engineering gene products hair biology hair growth hair structure hair cycle sebaceous glands genetic modification genes

TLDR Mutant mice help researchers understand hair growth and related genetic factors.

The document reviewed various mutant mice with hair abnormalities, categorized into six types: low hair follicle numbers, hair morphogenesis disorders, hair follicle cycling disorders, hair follicle structure disorders, sebaceous gland structure disorders, and hair growth disorders due to immunological issues. The increasing number of such mutants, due to advanced genetic engineering, provided insights into the roles of many gene products in hair biology. An annotated table was provided to help researchers understand molecular controls of hair growth and compare new mouse models with existing ones.

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