2 citations
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September 2022 in “American Journal of Clinical Dermatology” 2 citations
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August 2022 in “Aesthetic Plastic Surgery” 2 citations
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December 2021 in “Dermatology and therapy” This review reports that clinical studies generally showed favorable results for microneedling as an adjunct therapy for androgenic alopecia and alopecia areata, despite the low quality of existing data.
5 citations
,
August 2021 in “The Journal of the American Animal Hospital Association/Journal of the American Animal Hospital Association” This study observed that accidental topical minoxidil exposure can cause toxicosis in dogs and cats, leading to moderate or major illness, and even death in some cats.
16 citations
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June 2021 in “Journal of Dermatological Treatment” This study reported that while topical minoxidil exhibits hair regrowth in androgenetic alopecia, oral minoxidil 5 mg/day was more effective than topical forms after six months, with low doses also potentially effective for women and other hair loss types.
39 citations
,
February 2021 in “Journal of The American Academy of Dermatology” In this study, low-dose oral minoxidil for hair loss was associated with infrequent systemic adverse effects, and only 1.7% of patients discontinued treatment due to these effects.
24 citations
,
January 2021 in “Dermatologic Therapy” This review found that platelet-rich plasma therapy improved hair growth and thickness in most studies on alopecia, with the highest improvement seen when combined with Minoxidil.
53 citations
,
August 2019 in “Journal of The American Academy of Dermatology” This study observed that low-dose oral minoxidil and topical minoxidil 5% solution both improved hair density in women with female-pattern hair loss, but oral minoxidil may offer advantages in reducing hair shedding.
27 citations
,
June 2019 in “Aesthetic Plastic Surgery” Platelet-Rich Plasma (PRP) treatment may increase hair growth for genetic hair loss, but more research is needed to confirm this.
36 citations
,
September 2018 in “Dermatologic Therapy” This study found that 78% of patients continued taking oral minoxidil for androgenetic or traction alopecia, with 33% reporting decreased hair shedding and 28% noting increased scalp hair.
18 citations
,
October 2017 in “PLOS ONE” This study found that in Pomeranians with Alopecia X, key genes in the Wnt and Shh signaling pathways and stem cell markers are downregulated, which may explain the absence of anagen hair follicles.
48 citations
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January 2017 in “International Journal of Trichology” This study found that combining microneedling with PRP and topical minoxidil (5%) significantly improved hair growth in men with androgenetic alopecia compared to using minoxidil alone.
55 citations
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January 2016 in “Annals of Dermatology” This study found that repeated microneedle stimulation in mice promoted hair growth and increased the expression of hair-growth-related genes, suggesting potential therapeutic uses for alopecia.
12 citations
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July 2015 in “Veterinary Dermatology” This study observed that microneedling induced significant hair regrowth and reduced hyperpigmentation in two Pomeranians with alopecia X, with stable results over 12 months.
10 citations
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July 2014 in “Veterinary dermatology” This study found that deslorelin may promote hair regrowth in intact male dogs with hair cycle arrest, but had no effect on neutered females.
10 citations
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September 2013 in “Veterinary dermatology” This study found that medroxyprogesterone injections led to partial or complete hair regrowth in some Pomeranian dogs with alopecia X, though their IGF-1 levels remained unchanged.
28 citations
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May 2012 in “Veterinary Dermatology” In this study, dogs with hair cycle disorders, especially those with alopecia X, showed a significant increase in the number of kenogen follicles, suggesting impaired induction of new hair growth phases.
81 citations
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April 2009 in “Journal of Investigative Dermatology” This review discusses the shedding phase of the hair cycle, known as exogen, and reports no new findings while analyzing related processes like club fiber formation and release.
11 citations
,
January 2007 in “Veterinary dermatology” This study found that administerating 10 mg/kg intramuscular fulvestrant did not stimulate hair regrowth in Pomeranian dogs with alopecia X, though higher doses may warrant further investigation.
32 citations
,
November 2006 in “Veterinary dermatology” This review discusses the various forms of congenital alopecia in domestic animals and highlights the need for improved classification due to limited understanding and rarity; it reports no new clinical results.
15 citations
,
September 2005 in “The Journal of the American Animal Hospital Association/Journal of the American Animal Hospital Association” This study found that trilostane treatment led to complete hair regrowth in three Alaskan malamutes with ACTH-stimulated elevated 17-hydroxyprogesterone levels within 6 months without any recognized adverse effects.
21 citations
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May 2005 in “Journal of the American Veterinary Medical Association” The exact cause of growth hormone-responsive alopecia in dogs is unclear.
40 citations
,
October 2004 in “Veterinary Dermatology” In this study, trilostane treatment led to complete hair re-growth in 85% of Pomeranians and all miniature poodles with alopecia X within 4 to 8 weeks.
52 citations
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October 2004 in “Veterinary dermatology” This study found that 62% of neutered dogs with hair cycle arrest experienced partial to complete hair re-growth after melatonin treatment, but hair re-growth was not consistently linked to normal sex hormone levels.
63 citations
,
April 2003 in “Journal of The European Academy of Dermatology and Venereology” This study found that minoxidil topical solution was associated with a dose-related occurrence of hypertrichosis, especially facial hair, in women treated for androgenetic alopecia.
31 citations
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October 2002 in “Dermatologic Surgery” This article reviews expert opinions on combining pharmacologic treatments like minoxidil with hair transplantation, reporting improved hair density and regrowth in patients with partially functioning follicles.
107 citations
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September 2002 in “Journal of Investigative Dermatology” This study identified a distinct "exogen" phase in the hair cycle during which hair shedding occurs, primarily coupled with the anagen phase, rather than as part of the telogen phase.
149 citations
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June 2002 in “Veterinary record/The veterinary record” This study found that trilostane was effective in resolving symptoms such as polyuria and polydipsia in many dogs with pituitary-dependent hyperadrenocorticism, with significant hormone level reductions observed.
116 citations
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April 2002 in “American journal of veterinary research” This study found trilostane to be an effective and generally safe treatment for improving symptoms in dogs with pituitary-dependent hyperadrenocorticism.
123 citations
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February 2002 in “Journal of The American Academy of Dermatology” Minoxidil can cause skin allergy; use alternative solvents or treatments if allergic.
40 citations
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July 1995 in “Toxicologic Pathology” In this study, glyburide prevented or significantly reduced cardiovascular lesions in dogs caused by minoxidil by blocking its hemodynamic effects, suggesting the toxicity is related to these profound effects rather than direct heart toxicity.
7 citations
,
January 1990 in “Clinical and Experimental Dermatology” This study observed that without any treatment, hair counts did not increase, suggesting that counting methods are unlikely to explain the 'placebo-effect' seen in previous minoxidil studies.
23 citations
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October 1988 in “Clinics in Dermatology” Minoxidil was first made for high blood pressure, but it was later found to help hair growth.
34 citations
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September 1985 in “Contact Dermatitis” Minoxidil can cause skin irritation like eczema and rash in some users.
96 citations
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October 1981 in “Drugs” Minoxidil effectively treats severe hypertension but may cause side effects, so careful monitoring is needed.
