Impact and Management of Loss of Eyebrows and Eyelashes

May 2023 in “ Dermatology and therapy ”

Michela Starace, Stephano Cedirian, Aurora Alessandrini, Francesca Bruni, Federico Quadrelli, Daniel Fernandes Melo, Tatiana Silyuk, А. G. Doroshkevich, Bianca Maria Piraccini, Matilde Iorizzo

madarosis eyebrow loss eyelash loss diagnosis treatment options

Studysummary This study aims to provide a practical guide for managing common causes of madarosis, highlighting the need to identify underlying causes to ensure effective treatment for eyelash and eyebrow loss.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

The document discusses the importance of eyelashes and eyebrows, highlighting their protective role for the eyes and their contribution to facial expression. It acknowledges that the loss of these hairs, known as madarosis, can significantly affect a person's quality of life both functionally and psychologically. The paper emphasizes the necessity of determining the cause of madarosis to provide effective treatment and aims to offer a practical guide for managing the most common causes of this condition. The summary suggests that the document provides detailed information on diagnosis and treatment options for those experiencing loss of eyebrows and eyelashes, with the goal of improving patient care in these cases.

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Research cited in this study

29 / 29 results

research Eyebrow and Eyelash Alopecia: A Clinical Review

6 citations , October 2022 in “American journal of clinical dermatology”

This review provides an updated overview of the symptomatology, diagnosis, trichoscopy findings, and treatment options for eyebrow and eyelash alopecia, but it reports no new experimental results.

research Isolated Hair Loss on the Eyebrow: Five Cases with Trichoscopic Features

1 citations , March 2022 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia”

This study found that trichoscopy is a useful tool in differentiating between alopecia areta and trichotillomania on the eyebrows based on distinct hair and follicle features.

research A Comprehensive Literature Review of JAK Inhibitors in the Treatment of Alopecia Areata

40 citations , June 2021 in “Clinical, cosmetic and investigational dermatology”

This review explores the efficacy and outcomes of using JAK inhibitors for treating alopecia areata, noting advancements in understanding the disease's pathomechanisms and suggesting that JAK inhibitors may offer targeted therapeutic benefits by blocking specific inflammatory pathways involved in this chronic condition.

research Topical Tofacitinib for the Treatment of Alopecia Areata Affecting Facial Hair

7 citations , April 2021 in “British Journal of Dermatology”

In this research letter from the British Journal of Dermatology, the authors explore the use of topical tofacitinib to treat alopecia areata affecting facial hair, but specific results are not reported in the abstract.

research Italian Guidelines in Diagnosis and Treatment of Alopecia Areata

37 citations , December 2019 in “Giornale italiano di dermatologia e venereologia”

This Italian guideline discusses the diagnosis and treatment of alopecia areata but reports no new clinical trial results; the authors highlight the need for well-designed studies.

research Frontal Fibrosing Alopecia: An Update on Pathogenesis, Diagnosis, and Treatment

61 citations , January 2019 in “American Journal of Clinical Dermatology”

This review discusses the potential causes and treatments for frontal fibrosing alopecia but reports no new clinical findings, highlighting the need for further research to understand its pathogenesis and develop validated treatments.

research Topical Tofacitinib Solution for the Treatment of Alopecia Areata Affecting Eyelashes

24 citations , October 2018 in “JAAD Case Reports”

This paper reviews the challenges of treating alopecia areata affecting eyelashes and discusses the risks associated with traditional therapies; it reports no new clinical results.

research Treatment of Alopecia Universalis with Topical Janus Kinase Inhibitors – A Double Blind, Placebo, and Active Controlled Pilot Study

49 citations , August 2018 in “International Journal of Dermatology”

In this phase I study, partial hair regrowth was observed in patients with alopecia universalis using topical JAK inhibitors, though more research is needed to confirm potential as a treatment alternative to clobetasol.

research Madarosis: A Qualitative Study to Assess Perceptions and Experience of Australian Patients with Early Breast Cancer Treated with Taxane-Based Chemotherapy

11 citations , August 2017 in “Supportive care in cancer”

This study highlights the significant impact of eyebrow and eyelash loss during chemotherapy on women's quality of life, noting both emotional and physical challenges.

research Bimatoprost for the Treatment of Eyelash, Eyebrow, and Scalp Alopecia

38 citations , March 2017 in “Expert Opinion on Investigational Drugs”

This review examines the potential of bimatoprost for treating various types of eyelash and eyebrow hypotrichosis, discussing its pharmacological properties but providing no new clinical results.

research Isolated Eyebrow Loss in Frontal Fibrosing Alopecia: Relevance of Early Diagnosis and Treatment

27 citations , May 2016 in “British journal of dermatology/British journal of dermatology, Supplement”

research An Evaluation of the Safety and Efficacy of Bimatoprost for Eyelash Growth in Pediatric Subjects

16 citations , March 2016 in “Clinical ophthalmology”

In this study, bimatoprost 0.03% was effective and well-tolerated for improving eyelash hypotrichosis in healthy adolescents, but not for those with the condition due to chemotherapy or alopecia areata.

research Topical Ruxolitinib for the Treatment of Alopecia Universalis

96 citations , December 2015 in “JAMA dermatology”

This article discusses the potential of topical ruxolitinib as a treatment for alopecia universalis and acknowledges the need for alternatives to systemic JAK inhibitors due to the risk of serious side effects.

research Madarosis, Milphosis, Eyelash Trichomegaly, and Dermatochalasis: Conditions Affecting the Periocular Area

10 citations , February 2015 in “Clinics in Dermatology”

This article discusses various periocular conditions like madarosis, milphosis, trichomegaly, and dermatochalasis, and highlights their potential link to underlying local and systemic diseases, but reports no new clinical findings.

Efficacy and Safety of Diphenylcyclopropenone Alone or in Combination with Anthralin in the Treatment of Chronic Extensive Alopecia Areata: A Retrospective Case Series

research Efficacy and Safety of Diphenylcyclopropenone Alone or in Combination with Anthralin in the Treatment of Chronic Extensive Alopecia Areata: A Retrospective Case Series

44 citations , February 2015 in “Journal of the American Academy of Dermatology”

This study found that combination therapy with diphenylcyclopropenone and anthralin was more effective for complete hair regrowth in chronic extensive alopecia areata than diphenylcyclopropenone alone, despite more common side effects.

research Frontal Fibrosing Alopecia: A Multicenter Review of 355 Patients

339 citations , February 2014 in “Journal of The American Academy of Dermatology”

This study found that eyelash loss, facial papules, and body hair involvement were linked to severe frontal fibrosing alopecia, and antiandrogens were the most effective treatment.

research Eyelash Alopecia Areata: Case Series and Literature Review

11 citations , August 2012 in “Canadian journal of ophthalmology”

This study found that among patients with eyelash alopecia areata, 40% experienced complete regrowth of lashes, with a mean time to regrowth of 28 months.

research Eyebrow Regrowth in Patients with Frontal Fibrosing Alopecia Treated with Intralesional Triamcinolone Acetonide

51 citations , August 2010 in “British journal of dermatology/British journal of dermatology, Supplement”

In this study, intralesional triamcinolone acetonide was associated with eyebrow regrowth in some patients with frontal fibrosing alopecia.

research Alopecia Areata Update

244 citations , January 2010 in “Journal of the American Academy of Dermatology”

This review discusses treatment options for alopecia areata and suggests tailored treatment plans, noting the challenges posed by spontaneous remission and limited high-quality clinical trials.

research Bimatoprost in the Treatment of Eyelash Universalis Alopecia Areata

37 citations , January 2010 in “International Journal of Trichology”

In this 1-year study of patients with alopecia areata universalis, researchers found that 0.03% topical bimatoprost led to an acceptable cosmetic response in 43.24% of participants.

research Latanoprost in the Treatment of Eyelash Alopecia in Alopecia Areata Universalis

50 citations , December 2009 in “Journal of The European Academy of Dermatology and Venereology”

This study found that latanoprost may be effective for treating eyelash alopecia areata, achieving cosmetically acceptable regrowth in 45% of patients.

Lack of Efficacy of Topical Latanoprost and Bimatoprost Ophthalmic Solutions in Promoting Eyelash Growth in Patients with Alopecia Areata

research Lack of Efficacy of Topical Latanoprost and Bimatoprost Ophthalmic Solutions in Promoting Eyelash Growth in Patients with Alopecia Areata

55 citations , March 2009 in “Journal of The American Academy of Dermatology”

This study found that latanoprost and bimatoprost, when applied cutaneously to the eyelids, did not induce appreciable eyelash regrowth in patients with alopecia areata over 16 weeks.

research Alopecia Areata of Eyelashes: Regrowth After Injecting Triamcinolone Into the Eyebrow Area

2 citations , February 2009 in “Journal of the American Academy of Dermatology”

Injecting triamcinolone into the eyebrow area may help eyelash regrowth in alopecia areata patients.

research The Surgical Treatment of Cicatricial Alopecia

51 citations , July 2008 in “Dermatologic Therapy”

This article proposes two new categories of cicatricial alopecia—“unstable” and “stable”—and suggests surgical excision as preferred over hair transplantation, especially for unstable cases.

research Isolated Eyebrow And Eyelash Trichotillomania Mimicking Alopecia Areata

27 citations , February 2006 in “International Journal of Dermatology”

This study concluded that isolated trichotillomania of the eyebrows and eyelashes, identified by specific hair characteristics, may be linked to underlying obsessive-compulsive disorders in affected patients.

research Lack of Efficacy of Topical Latanoprost in the Treatment of Eyebrow Alopecia Areata

36 citations , November 2005 in “Journal of The American Academy of Dermatology”

This article discusses the potential of latanoprost for treating alopecia areata, but notes that well-controlled studies are still needed to confirm its effectiveness.

research Efficacy of Topical Sensitizers in the Treatment of Alopecia Areata

132 citations , November 1998 in “Journal of the American Academy of Dermatology”

This review evaluates the efficacy and safety of topical sensitizers in treating alopecia areata but reports no new clinical findings.

research Postmenopausal Frontal Fibrosing Alopecia

325 citations , June 1994 in “Archives of Dermatology”

This study observed that progressive frontal recession in postmenopausal women may exhibit features of fibrosing alopecia, suggesting a distinct reaction pattern from typical lichen planopilaris.

research Postmenopausal Frontal Fibrosing Alopecia: Scarring Alopecia in a Pattern Distribution

332 citations , June 1994 in “Archives of Dermatology”

This study found that progressive frontal hairline recession in postmenopausal women may exhibit features similar to fibrosing alopecia, with histologic similarities to lichen planopilaris but lacking lesions of lichen planus.