Impact of Systemic Hormonal Imbalances on Sebaceous Gland Disorders: An In-Depth Review Integrating Clinical, Endocrine, and Therapeutic Insights

    August 2026 in “ Cosmoderma ”
    A. K. M. R. Islam, Riddhi Nayankumar Adhyaru, Harsahaj Singh Wilkhoo … Sahil Ankush Chavan
    Studysummary This review identifies sebaceous gland disorders as key indicators of hormonal imbalances, detailing how various hormones affect sebaceous function, and emphasizes a multidisciplinary approach to improve diagnosis and management by integrating endocrine, metabolic, and dermatologic insights.
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    Research cited in this study 11

    1. A Narrative Review on Cutaneous Manifestations in Polycystic Ovary Syndrome: Pathophysiology, Diagnosis, Management, and Psychosocial Impact Annals of Medicine and Surgery · 2025
    2. Hormonal Therapies for Acne: A Comprehensive Update for Dermatologists Dermatology and Therapy · 2025
    3. Skin Barrier Dysfunction in Acne Vulgaris: Pathogenesis and Therapeutic Approaches Medical Science Monitor · 2024
    4. Prolactin: A Mammalian Stress Hormone and Its Role in Cutaneous Pathophysiology International Journal of Molecular Sciences · 2024
    5. Unveiling the Nuances of Adult Female Acne: A Comprehensive Exploration of Epidemiology, Treatment Modalities, Dermocosmetics, and the Menopausal Influence International journal of women's health · 2024
    6. Dermatologic Care of Patients With Differences of Sex Development International Journal of Women’s Dermatology · 2023
    7. Aging in the Sebaceous Gland Frontiers in Cell and Developmental Biology · 2022
    8. An Updated Review of the Sebaceous Gland and Its Role in Health and Diseases Part 2: Pathophysiological Clinical Disorders of Sebaceous Glands Dermatologic Therapy · 2021
    9. Dermatologic Manifestations of Endocrine Disorders Translational pediatrics · 2017
    10. Survivin as a Novel Biomarker in the Pathogenesis of Acne Vulgaris and Its Correlation to Insulin-Like Growth Factor-I Disease Markers · 2016
    11. Thyroid Hormone Action on Skin Dermato-endocrinology · 2011