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    Alteration of Hair Growth in Mice by Circulating Exosomes from Xinji Fine-Wool and Small-Tailed Han Sheep

    April 2025 in “ Frontiers in Animal Science ”
    Xinyu Zhang, Wei Wang, Wei Fan … Fuliang Sun
    Studysummary In this study, researchers found that circulating exosomes from different sheep breeds can significantly alter hair growth in mice, with the source of exosomes influencing hair follicle size and hair diameter, as well as expression of specific hair growth and melanin synthesis markers.
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    Research cited in this study 13

    1. Stimulation of Mouse Hair Regrowth by Exosomes Derived from Human Umbilical Cord Mesenchymal Stem Cells Acta Histochemica · 2024
    2. Shh Gene Regulates Proliferation and Apoptosis of Dermal Papilla Cells in Secondary Hair Follicle Growth Cycle of Cashmere Goats Animals · 2024
    3. MiR-199a-3p Regulates the PTPRF/β-Catenin Axis in Hair Follicle Development: Insights into the Pathogenic Mechanism of Alopecia Areata International journal of molecular sciences · 2023
    4. Hair Follicle Development of Rex Rabbits Is Regulated Seasonally by Wnt10b/β-Catenin, TGFβ-BMP, IGF1, and EGF Signaling Pathways Animals · 2023
    5. Hair Follicle Transcriptome Analysis Reveals Genes Regulating Wool Fiber Diameter in Angora Rabbits Biology · 2023
    6. Efficacy of Autologous Platelet-Rich Plasma Therapy Versus Topical Minoxidil in Men With Moderate Androgenetic Alopecia: A Randomized Open-Label Trial Journal of Dermatological Treatment · 2023
    7. Expression Profile of Long Non-Coding RNA in Inner Mongolian Cashmere Goat With Putative Roles in Hair Follicles Development Frontiers in veterinary science · 2022
    8. Effects of Adipose-Derived Stem Cells and Platelet-Rich Plasma Exosomes on the Inductivity of Hair Dermal Papilla Cells PubMed · 2021
    9. Platelet-Rich Plasma and Cell Therapy Dermatologic clinics · 2021
    10. Evidence from a Humanized Mouse Model of Androgenetic Alopecia That Platelet-Rich Plasma Stimulates Hair Regrowth, Hair Shaft Diameter, and Vellus-to-Terminal Hair Reconversion In Vivo British Journal of Dermatology · 2021
    11. MiRNA Microarray Profiling in Patients with Androgenic Alopecia and the Effects of miR-133b on Hair Growth Experimental and Molecular Pathology · 2020
    12. Dermal Exosomes Containing miR-218-5p Promote Hair Regeneration by Regulating β-Catenin Signaling Science Advances · 2020
    13. Biology of the Wool Follicle: An Excursion into a Unique Tissue Interaction System Waiting to Be Rediscovered Experimental Dermatology · 2006