CXXC5 Mediates DHT-Induced Androgenetic Alopecia via PGD2
February 2023
in “Cells”
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research Androgenetic alopecia: combing the hair follicle signaling pathways for new therapeutic targets and more effective treatment options
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research Androgen modulation of Wnt/β-catenin signaling in androgenetic alopecia
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research Targeting of CXXC5 by a Competing Peptide Stimulates Hair Regrowth and Wound-Induced Hair Neogenesis
Blocking a protein called CXXC5 with a specific peptide can stimulate hair regrowth and new hair growth in wounds.

research Androgens modify Wnt agonists/antagonists expression balance in dermal papilla cells preventing hair follicle stem cell differentiation in androgenetic alopecia
Androgens prevent hair growth by changing Wnt signals in cells.

research Topical application of the Wnt/β-catenin activator methyl vanillate increases hair count and hair mass index in women with androgenetic alopecia
Methyl vanillate spray increases hair count and hair mass in women with hair loss.

research Topical valproic acid increases the hair count in male patients with androgenetic alopecia: A randomized, comparative, clinical feasibility study using phototrichogram analysis
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research Cause of Androgenic Alopecia
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research Prostaglandin D2 Inhibits Wound-Induced Hair Follicle Neogenesis through the Receptor, Gpr44

research Hair follicle stem cell differentiation is inhibited through cross‐talk between Wnt/β‐catenin and androgen signalling in dermal papilla cells from patients with androgenetic alopecia
Androgens block hair growth by disrupting cell signals; targeting GSK-3 may help treat hair loss.

research Minoxidil Use in Dermatology, Side Effects and Recent Patents
Minoxidil treats hair loss, promotes growth, has side effects, and has recent patents.

research Prostaglandin D 2 Inhibits Hair Growth and Is Elevated in Bald Scalp of Men with Androgenetic Alopecia
PGD2 stops hair growth and is higher in bald men with AGA.
research Characterization and quantification of wound-induced hair follicle neogenesis using in vivo confocal scanning laser microscopy

research A Mouse Model of Androgenetic Alopecia
Mice with human gene experienced hair loss when treated with DHT.

research The Hair Follicle as a Dynamic Miniorgan
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research Dihydrotestosterone-Inducible Dickkopf 1 from Balding Dermal Papilla Cells Causes Apoptosis in Follicular Keratinocytes

research Wnt-dependent de novo hair follicle regeneration in adult mouse skin after wounding
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research Androgenetic Alopecia in Women
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