Distinct Expression Profile of Stem Cell Markers, LGR5 and LGR6, in Basaloid Skin Tumors

    January 2017 in “ Virchows Archiv ”
    Bo Gun Jang, Cheol Lee, Hye Sung Kim … Woo Ho Kim
    Studysummary This study documented distinct expression patterns of stem cell markers LGR5 and LGR6 in various human skin tumors, highlighting differences in their potential roles and contributions to tumor development.
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    Research cited in this study 4

    1. Basal Cell Carcinoma: Molecular Biology and Potential New Therapies Journal of Clinical Investigation · 2012
    2. Wnt Signaling, Lgr5, and Stem Cells in the Intestine and Skin ˜The œAmerican journal of pathology · 2009
    3. Lgr5 Marks Cycling, Yet Long-Lived, Hair Follicle Stem Cells Nature Genetics · 2008
    4. Cytokeratins as Markers of Follicular Differentiation American Journal of Dermatopathology · 2001

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    3. Paneth Cells in Intestinal Homeostasis and Tissue Injury PLoS ONE · 2012
    4. Wnt Signaling, Lgr5, and Stem Cells in the Intestine and Skin ˜The œAmerican journal of pathology · 2009
    5. Lgr5 Marks Cycling, Yet Long-Lived, Hair Follicle Stem Cells Nature Genetics · 2008
    6. Multi-Potentiality of a New Immortalized Epithelial Stem Cell Line Derived from Human Hair Follicles In vitro cellular & developmental biology. Animal · 2008
    7. C-Myc Activation in Transgenic Mouse Epidermis Results in Mobilization of Stem Cells and Differentiation of Their Progeny Current Biology · 2001