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GlossaryPilomatricoma

benign skin tumor originating from hair follicle matrix cells

Pilomatricoma, also known as Calcifying Epithelioma of Malherbe or Pilomatrixoma, is a benign skin tumor that originates from hair follicle matrix cells. It typically presents as a firm, painless lump under the skin, often on the face, neck, or arms, and can sometimes become calcified. While it is generally non-cancerous, surgical removal is usually recommended to prevent potential complications.

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research Activation of the OVOL1-OVOL2 Axis in the Hair Bulb and Pilomatricoma

20 citations, February 2016 in “American Journal of Pathology”

The genes OVOL1 and OVOL2 are important for hair growth and may be involved in a type of skin tumor.

research Pilomatricoma Arising at a BCG Vaccination Site

13 citations, February 2006 in “Clinical and Experimental Dermatology”

A benign tumor developed at a girl's BCG vaccination site, not previously linked to the vaccine.

research Spatial Transcriptomics of a Giant Pilomatricoma

1 citations, August 2023 in “Journal of cutaneous pathology”

The analysis of a large pilomatricoma revealed five distinct areas with different gene activity related to hair growth and tumor development.

research Pilomatricoma With Florid Osseous Metaplasia: A Cytologist’s Perspective

April 2024 in “Journal of Cytology”

A rare skin tumor with bone formation was successfully removed without recurrence.

research Pilomatricoma on the Abdomen with Overlying Striae Distensae: A Unique Presentation

January 2024 in “Skin”

A rare case of a benign hair follicle tumor with unusual skin changes highlights the need for timely diagnosis to prevent potential cancer.

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