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Glossary Ghost Cells

non-viable cells appearing as pale, shadowy outlines

Ghost cells are non-viable cells that have lost their nuclei and cytoplasmic details, often appearing as pale, shadowy outlines under a microscope. They are commonly seen in certain pathological conditions, such as pilomatricoma, a type of benign skin tumor, where they result from the degeneration of hair matrix cells.

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Research

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research Expression pattern of human hair keratin basic 1 (hHbl) in hair follicle and pilomatricoma

8 citations , April 1997 in “Experimental Dermatology”

This study found that hHbl gene expression is localized in the cortical cells of the human hair shaft and is notably high in pilomatricoma cells transitioning to hair shaft keratinocytes.

research Follicular Hybrid Cyst With Isthmic-Catagen, Pilomatrical, and Syringocystadenoma Papilliferum Components

2 citations , June 2012 in “American Journal of Dermatopathology”

This case study describes a rare cutaneous follicular hybrid cyst intimately associated with syringocystadenoma papilliferum, proposing a potential relationship with the infrainfundibulum based on keratin expression.

research Bullous pilomatrixoma: Without a “Shadow” of doubt – Role of ROSE and cytology

1 citations , January 2022 in “Indian dermatology online journal”

This case report documents the presentation and diagnosis of a rare bullous pilomatrixoma in a 20-year-old female using fine needle aspiration cytopathology, highlighting diagnostic challenges and features.

research Pilomatricoma with Florid Osseous Metaplasia: A Cytologist’s Perspective

April 2024 in “Journal of Cytology”

In this case study, researchers describe a rare instance of pilomatricoma with ossification in a 32-year-old woman, highlighting specific histopathological features and the role of bone morphogenic proteins and macrophages in its development.

research Solitary, subcutaneous, fixed, firm, and fast-growing nodule

March 2022 in “JAAD case reports”

A man had a non-cancerous, fast-growing skin lump on his arm that was removed with surgery.

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community If pp405 isnt the “cure” is there anything else that’s promising thats atleast better than min or dut?

20 upvotes 5 months ago

Hair cloning and new treatments like ET-02, Veradermics (vdphl01), and wound-induced hair neogenesis show promise but are not yet widely available. Current effective treatments include minoxidil, finasteride, and dutasteride, with early intervention being crucial for better outcomes.

community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

63 upvotes 2 years ago

Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

community What to do if fin is still not working after 2.5 years

in Finasteride/Dutasteride 22 upvotes 1 year ago

The user is experiencing increased hair loss despite using finasteride and oral minoxidil and is hesitant to switch to dutasteride due to side effects and family planning concerns. Alternatives suggested include dutasteride, microneedling, and addressing stress or nutrient deficiencies.

community fin 0.5 mg everday 6 months update

in Finasteride/Dutasteride 28 upvotes 2 years ago

The post discusses the experiences of individuals with diffuse hair thinning using finasteride, with many reporting no improvement or worsening conditions after 6 months. Various suggestions include persisting with the treatment, checking for underlying conditions, adding minoxidil for volume, adjusting dosage, and considering other potential causes like autoimmune responses and inflammation.

community Fin isn’t working anymore after 3 years, afraid to switch to dut?

in Finasteride/Dutasteride 27 upvotes 2 years ago

Finasteride stopped working for a user after 3 years, and they are considering switching to dutasteride. Other users suggest trying dutasteride, with some sharing positive experiences and additional treatments like minoxidil and RU58841.

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