Lactic Acid
Research
20 / 1000+ resultsresearch Novel Placenta-Derived Liquid Product Suitable for Cosmetic Application Produced by Fermentation and Digestion of Porcine or Equine Placenta Using Lactic Acid Bacterium Enterococcus Faecalis PR31
This study found that fermenting porcine and equine placentas with a specific lactic acid bacterial strain enhanced the moisturizing abilities and cell proliferation properties compared to traditional placental extracts, suggesting their potential for cosmetic applications.
research Traditional Chinese Medicine Shi-Bi-Man Regulates Lactic Acid Metabolism and Drives Hair Follicle Stem Cell Activation to Promote Hair Regeneration
This study found that Shi-Bi-Man significantly promotes hair regeneration in cynomolgus monkeys by increasing hair follicle stem cells and up-regulating metabolic pathways.
research Lactic Acid Bacteria as Probiotics Improve Bioactive Compounds in Radix Angelica Gigas (Danggui) via Solid-State Fermentation
This study found that solid-state fermentation using probiotic lactic acid bacteria significantly enhanced the antioxidant properties and bioactive composition of Radix Angelica gigas compared to non-fermented herbs, suggesting a potential method for modernizing traditional herbal medicine.
research Topical 15% Lactic Acid Solution Versus Topical Betamethasone Valerate Lotion in the Treatment of Multiple Patchy Alopecia Areata
This study concluded that topical betamethasone valerate lotion is more effective than topical 15% lactic acid solution for managing multiple patchy alopecia areata over a 12-week treatment period.
research Topical 15% Lactic Acid Solution Versus Topical Betamethasone Valerate Lotion in Treatment of Multiple Patchy Alopecia Areata
This study concluded that topical betamethasone valerate lotion is more effective than 15% lactic acid solution for managing multiple patchy alopecia areata over a 12-week period in a sample of 50 patients.
research Quantification of Squalene and Lactic Acid in Hair Bulbs with Damaged Sheaths: Are They Metabolic Wastes in Alopecia?
In this study, researchers found that subjects with clinical alopecia had significantly higher levels of squalene in their hair bulbs compared to controls, suggesting squalene as a potential metabolic and pathogenic marker for certain alopecia conditions.
research Natural Product Shi-Bi-Man Regulates Lactic Acid Metabolism and Drives Hair Follicle Stem Cell Activation to Promote Hair Regeneration
This study found that the natural product Shi-Bi-Man significantly promoted hair regeneration in cynomolgus monkeys, increasing hair follicle number and activation by boosting specific protein markers and interactions in Laminin-related pathways.
research Eruptive Vellus Hair Cysts Treated With Lactic Acid: Case Report and Review of the Literature
Lactic acid cream can help improve skin bumps known as eruptive vellus hair cysts.
research Evaluation of Lactic Acid Ferment Lysate for the Management of Oily Skin: Impact on Sebum, Hydration, and Microbiota
In this study, a topical cream containing 3% lactic acid ferment lysate (VHProbi ® MixP) was found to significantly reduce sebum, porphyrin levels, and pore size, while increasing hydration and improving skin texture in participants with oily skin over a 60-day period.
research Comparison of Three Different Lactic Acid Bacteria-Fermented Proteins on RAW 264.7 Osteoclast and MC3T3-E1 Osteoblast Differentiation
This study assessed three lactic acid bacteria-fermented proteins and found that F-WPI and F-SPI could normalize osteoclastogenesis markers in vitro, while F-SPI enhanced osteoblastogenesis markers, suggesting potential as dietary supplements for osteoporosis prevention, though further research into mechanisms is needed.
research Effect of Hyaluronic Acid and Poly-L-Lactic Acid Dermal Fillers on Collagen Synthesis: An In Vitro and In Vivo Study
This research found that hyaluronic acid increased cell proliferation and type I collagen more effectively than poly-L-lactic acid in both human fibroblast cultures and rat dermis.
research Development and Ex-Vivo Skin Permeation Studies of Finasteride–Poly(Lactic Acid-Co-Glycolic Acid) and Minoxidil–Chitosan Nanoparticulate Systems
This study found that finasteride- and minoxidil-loaded nanoparticles in a gel improved skin permeability and drug retention, suggesting a promising approach for topical alopecia treatment with reduced dosing frequency and side effects.
research Development and Characterization of Poly(Lactic-Co-Glycolic Acid) Nanoparticles With Finasteride and In Vivo Evaluation of Their Efficacy in Hair Growth
This study reported the successful development of finasteride-loaded poly(lactic-co-glycolic acid) nanoparticles, with varying encapsulation efficiencies, aiming to enhance drug delivery for hair growth while minimizing side effects, and noted that an in vivo study will follow to assess efficacy.
research Poly (Lactic-Co-Glycolic Acid)-Based Microneedles for Drug Delivery Across Different Biological Barriers
PLGA-based microneedles show promise for painless, long-term drug delivery but need design and safety improvements.
research Management of Visible Granulomas Following Periorbital Injection of Poly-L-Lactic Acid
This report describes a case of granulomatous reaction to injectable poly-L-lactic acid in the periorbital area and suggests surgical excision as an effective treatment for persistent nodules.
research Alopecia Induced by Poly-L-Lactic Acid Injection
PLLA injections can cause hair loss and skin issues.
research Poly-D,L-Lactic Acid Filler Restores Hair Thickness and Shine by Ameliorating Age-Associated Follicular Decline
This study found that PDLLA filler treatment may help combat age-related hair thinning by reducing oxidative stress and enhancing hair follicle function in both cell and animal models.
research Poly-D,L-Lactic Acid Filler Increases Hair Growth by Modulating Hair Follicular Stem Cells in Aged Skin
In this study, PDLLA treatment in middle-aged mice was observed to enhance hair growth by increasing macrophage M2 polarization and hair follicle stem cell proliferation, potentially rejuvenating the skin's microenvironment and offering a novel approach for age-related hair loss.
research Engineering a Skin-Mimicking Asymmetric Poly(L-Lactic Acid)/Gelatin Bioscaffold for Skin Repair
In this laboratory study, researchers developed a genipin-stabilized asymmetric PLA/gelatin scaffold that mimics skin architecture, supports fibroblast proliferation, and closes scratches effectively, suggesting its potential for epidermal-dermal regeneration and applications in sensing or drug delivery.
research Alopecia Secondary to Poly-L-Lactic Acid Dermal Fillers
In this study, researchers noted that while Poly-L-lactic acid dermal fillers boost collagen synthesis to add volume and reduce wrinkles, there is no established link between these fillers and hair loss according to existing literature.