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    Glossary Memory T Cells

    cells that remember past infections for faster future responses

    Memory T Cells, also known as Memory T Lymphocytes, are a type of immune cell that "remembers" past infections. After an initial encounter with a pathogen, these cells persist in the body and can quickly mount a strong immune response if the same pathogen is encountered again, providing long-term immunity. This is crucial for the effectiveness of vaccines and the body's ability to fight off repeated infections.

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    1. Skin CD4+ memory T cells exhibit combined cluster-mediated retention and equilibration with the circulation Nature communications · 2016 · 155 citations
    2. Cutting Edge: Memory Regulatory T Cells Require IL-7 and Not IL-2 for Their Maintenance in Peripheral Tissues 2013 · 140 citations
    3. Predominant expression of interleukin (IL)‐17 in chronic alopecia areata compared to IFN‐γ in pathogenic Th17 cells, tissue‐resident memory T cells and natural killer cells JEADV Clinical Practice · 2023 · 3 citations
    4. 083 More Expression of IL-17 than IFN-γ from CD49a-negative Tissue-Resident Memory T (Trm) cells at the Hair Bulge and Hair Bulb Region in the Scalp of Chronic Alopecia Areata Patients according to the Foxp3+mTregs depletion Journal of Investigative Dermatology · 2019
    5. 068 Pathogenic Th17 cells, CD8+CD69+CD49a- tissue-resident memory T cells and common γ chain receptor + natural killer cells express more IL-17, compared to IFN-γ, under the foxp3+ memory regulatory T cells-depleted microenvironment in patients with chronic alopecia areata Journal of Investigative Dermatology · 2023
    6. Hair follicle–derived IL-7 and IL-15 mediate skin-resident memory T cell homeostasis and lymphoma Nature medicine · 2015 · 245 citations
    7. Resident Memory T Cells in Autoimmune Skin Diseases Frontiers in immunology · 2021 · 50 citations
    8. Predominance of CD27-PD-1- Effector Memory T Cells Re-Expressing CD45RA Characterizes Treatment-Resistant Severe Alopecia Areata Journal of Investigative Dermatology · 2025 · 2 citations
    9. Human epidermal resident memory T cells: beyond the dermal perspective Frontiers in Immunology · 2026
    10. 0960 Evidence for resident memory T cells and necroptosis as drivers of fibrosis in eosinophilic fasciitis and morphea Journal of Investigative Dermatology · 2025
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