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    A Symphony of Signals: The Intricate Role of lncRNAs in Dermatological Disorders

    November 2025 in “ Clinical and Experimental Medicine ”
    Ahmad Ghorbani Vanan, Samaneh Nouri, Fatemeh Ghasabeh Hassanzadeh … Safa Tahmasebi
    Studysummary This review highlights the emerging role of long non-coding RNAs (lncRNAs) in dermatology, suggesting that lncRNAs significantly impact signaling pathways involved in normal skin functions and skin diseases, offering potential as biomarkers and therapeutic targets.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 11

    1. Identification of Potential Hub Genes in Alopecia Areata Experimental Dermatology · 2024
    2. LncRNA NEAT1 and miRNA 101 as Potential Diagnostic Biomarkers in Patients with Alopecia Areata Non-coding RNA Research · 2024
    3. Identification of Ferroptosis-Related Biomarkers in Alopecia Areata Through Machine Learning Scientific reports · 2024
    4. MiR-199a-3p Regulates the PTPRF/β-Catenin Axis in Hair Follicle Development: Insights into the Pathogenic Mechanism of Alopecia Areata International journal of molecular sciences · 2023
    5. Expression of Long Noncoding RNA HOTAIR and MicroRNA-205 and Their Relation to Transforming Growth Factor Beta 1 in Patients with Alopecia Areata Skin Appendage Disorders · 2023
    6. Evaluating the Role of lncRNAs in the Incidence of Cardiovascular Diseases in Androgenetic Alopecia Patients Cardiovascular Toxicology · 2022
    7. Alopecia Areata: An Update on Etiopathogenesis, Diagnosis, and Management Clinical Reviews in Allergy & Immunology · 2021
    8. Differential Expression Patterns of Specific Long Noncoding RNAs and Competing Endogenous RNA Network in Alopecia Areata Journal of Cellular Biochemistry · 2019
    9. The Role of PPARγ-Mediated Signalling in Skin Biology and Pathology: New Targets and Opportunities for Clinical Dermatology Experimental Dermatology · 2015
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    11. Alopecia Areata: An Autoimmune Disease Causing Hair Loss The New England Journal of Medicine · 2012