Expression of Long Noncoding RNA HOTAIR and MicroRNA-205 and Their Relation to Transforming Growth Factor Beta 1 in Patients with Alopecia Areata

    January 2023 in “ Skin Appendage Disorders ”
    Noha Ezzat Mohamad, Ahmed MB. Khedr, Olfat Shaker, Mohammed Hassan
    Studysummary This study found that patients with alopecia areata had higher serum levels of miRNA-205 and TGF-β1, but lower levels of lncRNA HOTAIR, suggesting a potential target for therapy.
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    Research cited in this study 5

    1. The Functions of Ocu-miR-205 in Regulating Hair Follicle Development in Rex Rabbits BMC Developmental Biology · 2020
    2. The Contributory Roles of Th17 Lymphocyte and Cytotoxic T Lymphocyte at the Hair Bulge Region and Hair Bulb Area in Chronic Alopecia Areata Patients Annals of dermatology/Annals of Dermatology · 2017
    3. Presence of Mast Cells and Mast Cell Degranulation in Scalp Biopsies of Telogen Effluvium International Journal of Trichology · 2017
    4. Epidemiology and Burden of Alopecia Areata: A Systematic Review Clinical, Cosmetic and Investigational Dermatology · 2015
    5. MicroRNAs in Skin Tissue Engineering Advanced drug delivery reviews · 2015