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Did you mean Long Non-Coding RNAs?

Glossary Long Non-Coding RNAs

regulate gene expression without coding for proteins

Long Non-Coding RNAs (lncRNAs) are a type of RNA molecule that are longer than 200 nucleotides and do not code for proteins. Instead, they play crucial roles in regulating gene expression, influencing processes such as cell differentiation, development, and disease mechanisms, including those related to hair growth and alopecia.

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Research

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research Biological Function of Long Non-coding RNA (LncRNA) Xist

247 citations , June 2021 in “Frontiers in Cell and Developmental Biology”

This review discusses the role of lncRNA Xist in cell growth regulation and disease development, particularly cancer, and reports no new experimental results.

research Analysis of histology and long noncoding RNAs involved in the rabbit hair follicle density using RNA sequencing

16 citations , January 2021 in “BMC Genomics”

This study found that high wool-producing Wan Strain Angora rabbits had higher hair follicle density and identified potential regulatory long noncoding RNAs that may influence this trait.

Long Noncoding RNA and Gene Expression Analysis of Melatonin-Exposed Liaoning Cashmere Goat Fibroblasts Indicating Cashmere Growth

research Long noncoding RNA and gene expression analysis of melatonin-exposed Liaoning cashmere goat fibroblasts indicating cashmere growth

12 citations , September 2018 in “Naturwissenschaften”

This study found that melatonin at 0.2 g/L for 72 hours most effectively enhances cashmere growth in Liaoning cashmere goats by upregulating the lncRNA MTC, which activates NF-kB signaling.

research Differential expression patterns of specific long noncoding RNAs and competing endogenous RNA network in alopecia areata

10 citations , February 2019 in “Journal of Cellular Biochemistry”

This study reports a complex network of blood lncRNA and associated pathways in alopecia areata but suggests further research is needed for verification and understanding of these findings.

research Expression of Long Noncoding RNA, HOTAIR, and MicroRNA-205 and Their Relation to Transforming Growth Factor β1 in Patients with Alopecia Areata

4 citations , January 2023 in “Skin Appendage Disorders”

This study found that patients with alopecia areata had higher serum levels of miRNA-205 and TGF-β1, but lower levels of lncRNA HOTAIR, suggesting a potential target for therapy.

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community Journey against alopecia - Finasteride 3 month

17 upvotes 4 years ago

A 26-year-old man from France started experiencing hair loss in September 2020 and began using finasteride in June 2021, reporting some improvement after three months without side effects. He plans to continue finasteride for a year before considering additional treatments like minoxidil or dermarolling.

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