Udenafil Induces the Hair Growth Effect of Adipose-Derived Stem Cells

    April 2019 in “ Biomolecules & Therapeutics ”
    Nahyun Choi, Jong Hwan Sung
    Studysummary This study found that udenafil-treated adipose-derived stem cells accelerated hair growth in mice by enhancing stem cell activity and growth factor secretion through the ERK and NFκB pathways.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on europepmc.org →
    Discuss this study in the Community →

    Research cited in this study 19

    1. IL-17 Inhibition: Is It the Long-Awaited Savior for Alopecia Areata? Archives of Dermatological Research · 2018
    2. Minoxidil Promotes Hair Growth Through Stimulation of Growth Factor Release from Adipose-Derived Stem Cells International Journal of Molecular Sciences · 2018
    3. Genetic Analysis of Interleukin 18 Gene Polymorphisms in Alopecia Areata Journal of Clinical Laboratory Analysis · 2018
    4. Hair Follicle Growth by Stromal Vascular Fraction-Enhanced Adipose Transplantation in Baldness Stem cells and cloning · 2017
    5. LL-37 Stimulates the Functions of Adipose-Derived Stromal/Stem Cells via Early Growth Response 1 and the MAPK Pathway Stem cell research & therapy · 2016
    6. Hair Regeneration Using Adipose-Derived Stem Cells PubMed · 2016
    7. Functional Regulation of Adipose-Derived Stem Cells by PDGF-D Stem Cells · 2014
    8. Isolation of Adipose-Derived Stem Cells Using a Subfractionation Culturing Method Expert Opinion on Biological Therapy · 2014
    9. The Molecular Mechanism Underlying the Proliferating and Preconditioning Effect of Vitamin C on Adipose-Derived Stem Cells Stem Cells and Development · 2014
    10. Ultraviolet B Preconditioning Enhances the Hair Growth-Promoting Effects of Adipose-Derived Stem Cells Via Generation of Reactive Oxygen Species Stem Cells and Development · 2012
    11. Adipocyte Lineage Cells Contribute to the Skin Stem Cell Niche to Drive Hair Cycling Cell · 2011
    12. Minoxidil Activates β-Catenin Pathway in Human Dermal Papilla Cells: A Possible Explanation for Its Anagen Prolongation Effect Journal of Dermatological Science · 2011
    13. Hair Growth Promoting Effects of Adipose Tissue-Derived Stem Cells Journal of Dermatological Science · 2009
    14. Hair Follicle Biology and Topical Minoxidil: Possible Mechanisms of Action Dermatology · 2009
    15. Effect of Minoxidil on Proliferation and Apoptosis in Dermal Papilla Cells of Human Hair Follicle Journal of Dermatological Science · 2004
    16. Hair Growth Effect of Minoxidil Folia Pharmacologica Japonica · 2002
    17. Minoxidil-Induced Hair Growth Is Mediated by Adenosine in Cultured Dermal Papilla Cells: Possible Involvement of Sulfonylurea Receptor 2B as a Target of Minoxidil Journal of Investigative Dermatology · 2001
    18. Activation of Cytoprotective Prostaglandin Synthase-1 by Minoxidil as a Possible Explanation for Its Hair Growth-Stimulating Effect Journal of Investigative Dermatology · 1997
    19. Minoxidil Stimulates Mouse Vibrissae Follicles in Organ Culture Journal of Investigative Dermatology · 1989

    Related research 1

    1. Dermis-Hair Follicle Communication: Extracellular Microvesicles Signaling for Hair Regeneration Journal of Investigative Dermatology · 2020