Comparative Genomics of the Keratin-Associated Protein Gene Clusters in Human, Chimpanzee, and Baboon

    March 2004 in “ Mammalian genome ”
    Kazunori Shibuya, Jun Kudoh, Izumi Obayashi … Nobuyoshi Shimizu
    Studysummary KAP genes are crucial for hair development and show both shared and unique traits in humans, chimpanzees, and baboons.
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    Research cited in this study 12

    1. A Cluster of 21 Keratin-Associated Protein Genes Within Introns of Another Gene on Human Chromosome 21q22.3 Genomics · 2004
    2. Characterization of a First Domain of Human High Glycine-Tyrosine and High Sulfur Keratin-Associated Protein Genes on Chromosome 21q22.1 Journal of biological chemistry/˜The œJournal of biological chemistry · 2002
    3. Cryo-Electron Microscopy of Trichocyte (Hard Alpha-Keratin) Intermediate Filaments Reveals a Low-Density Core Journal of Structural Biology · 2002
    4. Characterization of a Cluster of Human High/Ultrahigh Sulfur Keratin-Associated Protein Genes Embedded in the Type I Keratin Gene Domain on Chromosome 17q12-21 Journal of biological chemistry/˜The œJournal of biological chemistry · 2001
    5. Overexpression of Hoxc13 in Differentiating Keratinocytes Results in Downregulation of a Novel Hair Keratin Gene Cluster and Alopecia Development · 2001
    6. Pmg-1 and Pmg-2 Constitute a Novel Family of KAP Genes Differentially Expressed During Skin and Mammary Gland Development Mechanisms of Development · 1999
    7. Isolation and Characterization of a Putative Keratin-Associated Protein Gene Expressed in Embryonic Skin of Mice Journal of Investigative Dermatology · 1998
    8. Sequence Data and Chromosomal Localization of Human Type I and Type II Hair Keratin Genes Experimental Cell Research · 1995
    9. Regulation of Keratin Gene Expression in Hair Follicle Differentiation Annals of the New York Academy of Sciences · 1991
    10. An Ultrahigh-Sulphur Keratin Gene of the Human Hair Cuticle Is Located at 11q13 and Cross-Hybridizes with Sequences at 11p15 Mammalian Genome · 1991
    11. Structure and Expression of Genes for a Class of Cysteine-Rich Proteins of the Cuticle Layers of Differentiating Wool and Hair Follicles ˜The œjournal of cell biology/˜The œJournal of cell biology · 1990
    12. A Group of Type I Keratin Genes on Human Chromosome 17: Characterization and Expression Molecular and Cellular Biology · 1988