Human Placental Extract Exerts Hair Growth-Promoting Effects Through the GSK-3β Signaling Pathway in Human Dermal Papilla Cells

    August 2015 in “ International Journal of Molecular Medicine ”
    Tae‐Rin Kwon, Chang Taek Oh, Eui Yul Choi … Beom Joon Kim
    Studysummary This study found that human placental extract promoted hair growth and influenced cellular pathways in vitro and rat models, suggesting potential for future hair loss treatments.
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    Research cited in this study 13

    1. A Role of Placental Growth Factor in Hair Growth Journal of dermatological science · 2014
    2. Hair Loss and Herbs for Treatment Journal of Cosmetic Dermatology · 2013
    3. Valproic Acid Promotes Human Hair Growth in In Vitro Culture Model Journal of Dermatological Science · 2013
    4. Combination of Herbal Extracts and Platelet-Rich Plasma Induced Dermal Papilla Cell Proliferation: Involvement of ERK and Akt Pathways Journal of Cosmetic Dermatology · 2013
    5. Valproic Acid Induces Hair Regeneration in Murine Model and Activates Alkaline Phosphatase Activity in Human Dermal Papilla Cells PLOS ONE · 2012
    6. Minoxidil Use in Dermatology, Side Effects, and Recent Patents Recent Patents on Inflammation & Allergy Drug Discovery · 2012
    7. Persistent Sexual Side Effects of Finasteride for Male Pattern Hair Loss The Journal of Sexual Medicine · 2011
    8. Minoxidil Activates β-Catenin Pathway in Human Dermal Papilla Cells: A Possible Explanation for Its Anagen Prolongation Effect Journal of Dermatological Science · 2011
    9. Hair Growth Stimulatory Effect by a Combination of 5-Aminolevulinic Acid and Iron Ion International Journal of Dermatology · 2008
    10. Canonical WNT Signaling Promotes Mammary Placode Development and Is Essential for Initiation of Mammary Gland Morphogenesis Development · 2004
    11. Cyclical Changes in Rat Vibrissa Follicles Maintained In Vitro ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2000
    12. The Biology of Hair Follicles The New England Journal of Medicine · 1999
    13. The Secret Life of the Hair Follicle Trends in genetics · 1992

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