New Perspectives on Nutraceutical Insulin Sensitizing Agents in the Treatment of Psoriasis and Other Dermatological Diseases

    Pietro Morrone, Francesca Caroppo, Alberto De Pedrini … Germano Baj
    Studysummary This narrative review suggests that nutraceutical insulin-sensitizing agents like myo-inositol, alpha-lipoic acid, and vitamins may improve glycemic control and reduce inflammation in insulin resistance-related skin disorders; however, more robust long-term trials are needed to confirm these findings and establish treatment regimens.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 14

    1. Association of Myo-Inositol and Microlipodispersed Magnesium in Androgen-Dependent Dermatological Diseases: A Retrospective Study Pharmaceuticals · 2025
    2. Inflammatory Loops in the Epithelial-Immune Microenvironment of the Skin and Skin Appendages in Chronic Inflammatory Diseases Frontiers in immunology · 2023
    3. Comparing the Efficacy of Myo-Inositol Plus Alpha-Lactalbumin Versus Myo-Inositol Alone on Reproductive and Metabolic Disturbances of Polycystic Ovary Syndrome Metabolites · 2023
    4. The Role of Hormones in Hidradenitis Suppurativa: A Systematic Review International Journal of Molecular Sciences · 2022
    5. Sex Hormone-Binding Globulin as an Early Biomarker and Therapeutic Target in Polycystic Ovary Syndrome International Journal of Molecular Sciences · 2020
    6. What Causes Hidradenitis Suppurativa?—15 Years After Experimental Dermatology · 2020
    7. Efficacy and Safety of Tracnil Administration in Patients with Dermatological Manifestations of PCOS: An Open-Label Single-Arm Study Dermatology Research and Practice · 2020
    8. Metabolic Syndrome and Skin Diseases Frontiers in Endocrinology · 2019
    9. Efficacy of Combination Therapy of Inositols, Antioxidants, and Vitamins in Obese and Non-Obese Women with Polycystic Ovary Syndrome: An Observational Study Journal of Obstetrics and Gynaecology · 2019
    10. Homeostasis of the Sebaceous Gland and Mechanisms of Acne Pathogenesis British Journal of Dermatology · 2019
    11. Prolactin as a Candidate Sebotropic Hormone? Experimental Dermatology · 2018
    12. Insulin Resistance and Skin Diseases The Scientific World Journal · 2015
    13. Vitamin D and the Skin: Physiology and Pathophysiology Reviews in endocrine and metabolic disorders · 2011
    14. Efficacy of Myo-Inositol in the Treatment of Cutaneous Disorders in Young Women with Polycystic Ovary Syndrome Gynecological Endocrinology · 2009

    Related research 5

    1. The Impact of Hirsutism and Hypertrichosis on the Psychological State of Women with Polycystic Ovary Syndrome and Hyperandrogenism Applied Psychology Research · 2024
    2. Study of Cutaneous Manifestations of Polycystic Ovarian Syndrome International journal of reproduction, contraception, obstetrics and gynecology · 2020
    3. Of PCOS Symptoms, Hirsutism Has the Most Significant Impact on the Quality of Life of Iranian Women PLOS ONE · 2015
    4. Polycystic Ovary Syndrome and Acne Skin therapy letter · 2011
    5. Hirsutism Scoring in Polycystic Ovary Syndrome: Concordance Between Clinicians' and Patients' Self-Scoring Fertility and Sterility · 2010