Genetic Prediction of Male Pattern Baldness

    February 2017 in “ PLoS Genetics ”
    Saskia P. Hagenaars, W. David Hill, Sarah E. Harris … Riccardo E. Marioni
    Studysummary In this study, researchers used genetic data from over 52,000 men to identify over 250 genetic loci associated with severe hair loss and developed a predictive algorithm for determining hair loss risk.
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    Research cited in this study 20

    1. A Genome-Wide Association Scan in Admixed Latin Americans Identifies Loci Influencing Facial and Scalp Hair Features Nature Communications · 2016
    2. Hunting the Genes in Male-Pattern Alopecia: How Important Are They, How Close Are We and What Will They Tell Us? Experimental Dermatology · 2016
    3. Male Pattern Baldness in Relation to Prostate Cancer-Specific Mortality: A Prospective Analysis in the NHANES I Epidemiologic Follow-Up Study American Journal of Epidemiology · 2016
    4. Prediction of Male-Pattern Baldness from Genotypes European Journal of Human Genetics · 2015
    5. Evaluation of DNA Variants Associated with Androgenetic Alopecia and Their Potential to Predict Male Pattern Baldness PLOS ONE · 2015
    6. Alopecia and Its Association with Coronary Heart Disease and Cardiovascular Risk Factors: A Meta-Analysis International Journal of Cardiology · 2014
    7. Relationship Between Male Pattern Baldness and the Risk of Aggressive Prostate Cancer: An Analysis of the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial Journal of Clinical Oncology · 2014
    8. FGF5 Is a Crucial Regulator of Hair Length in Humans Proceedings of the National Academy of Sciences of the United States of America · 2014
    9. Evidence for a Polygenic Contribution to Androgenetic Alopecia British Journal of Dermatology · 2013
    10. Six Novel Susceptibility Loci for Early-Onset Androgenetic Alopecia and Their Unexpected Association with Common Diseases PLOS Genetics · 2012
    11. Susceptibility Variants on Chromosome 7p21.1 Suggest HDAC9 as a New Candidate Gene for Male-Pattern Baldness British Journal of Dermatology · 2011
    12. Androgenic Alopecia Is Not Useful as an Indicator of Men at High Risk of Prostate Cancer European Journal of Cancer · 2010
    13. Common Variants in the Trichohyalin Gene Are Associated with Straight Hair in Europeans American journal of human genetics · 2009
    14. Male-Pattern Baldness Susceptibility Locus at 20p11 Nature Genetics · 2008
    15. EDA2R Is Associated With Androgenetic Alopecia Journal of Investigative Dermatology · 2008
    16. Molecular Dissection of Mesenchymal–Epithelial Interactions in the Hair Follicle PLoS biology · 2005
    17. Genetic Variation in the Human Androgen Receptor Gene Is the Major Determinant of Common Early-Onset Androgenetic Alopecia American Journal of Human Genetics · 2005
    18. Genetic Basis of Male Pattern Baldness Journal of Investigative Dermatology · 2003
    19. Androgenetic Alopecia and Prostate Cancer: Findings from an Australian Case-Control Study PubMed · 2002
    20. The Psychosocial Consequences of Androgenetic Alopecia: A Review of the Research Literature British Journal of Dermatology · 1999

    Related research 8

    1. Androgenetic Alopecia: Overview, Diagnosis, and Treatment Springer eBooks · 2015
    2. Finasteride in the Treatment of Female Androgenic Alopecia PharmaTutor · 2014
    3. Daily Finasteride Boosts Hair Growth in Men Dermatology Times E-News · 2012
    4. Male Pattern Baldness: An Update Revista de Ciências Médicas · 2009
    5. Advances in the Treatment of Male Androgenetic Alopecia: A Brief Review of Finasteride Studies PubMed · 2001
    6. Fortnightly Review: Male Pattern Androgenetic Alopecia BMJ · 1998
    7. Male Pattern Alopecia: Impact on Self-Esteem and Evolution of Hair Restoration Surgery Dermatologic Clinics · 1997
    8. Biology of Scalp Hair Growth Clinics in Plastic Surgery · 1982