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Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

YAP and TAZ proteins are necessary for the development of two types of skin cancer.

Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.

Mice that can regenerate tissue have cells that pause in the cell cycle, which is important for healing, similar to axolotls.

The research provides a gene-based framework for hair biology, highlighting the Hippo pathway's importance and suggesting links between hair disorders, cancer pathways, and the immune system.

The conclusion suggests that PCOS may persist due to genetic traits that, while harmful for female fertility, could have provided survival and reproductive benefits to males.

Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.

Blocking YAP/TAZ could be a new way to treat skin cancer.

Proteomics combined with other technologies can lead to a better understanding of skin diseases.

The analysis of a large pilomatricoma revealed five distinct areas with different gene activity related to hair growth and tumor development.

Leptin-deficient mice, used as a model for Type 2 Diabetes, have delayed wound healing due to impaired contraction and other dysfunctional cellular responses.

Inaudible sound at 30 kHz can boost hair growth and decrease hair loss by promoting cell growth and reducing cell death in hair follicles.

Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.

A specific RNA molecule, circCOL1A1, affects the growth and quality of goat hair by interacting with miR-149-5p and influencing cell growth pathways.

MicroRNAs are crucial in controlling cell signaling, affecting cancer and tissue regeneration.

New markers and pathways have been found in skin tumors, helping better understand and diagnose them.

Found different long non-coding RNAs in balding Chinese men, which may help create new treatments.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.

The conclusion is that future hair loss treatments should target the root causes of hair thinning, not just promote hair growth.

Stem cell differentiation is crucial for skin barrier maintenance and its disruption can lead to skin diseases.

Wounds can regenerate hair in young mice, but this ability declines with age, offering insights for improving tissue regeneration in the elderly.

Different problems with hair stem cell renewal can lead to hair loss.

The we/we wal/wal mice have defects in hair growth and skin layer formation, causing hair loss, useful for understanding alopecia.

Lymphatic vessels are essential for health and can be targeted to treat various diseases.

Mechanical forces are crucial for shaping cells and forming tissues during development.

Effective PCOS treatments require targeting specific signaling pathways.

The Hedgehog signaling pathway is important for skin and hair growth and can lead to cancer if it doesn't work right.