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    Did you mean YAP/TAZ signaling?
    GlossaryYAP/TAZ signaling

    pathway controlling cell growth and development through specific proteins

    YAP/TAZ signaling refers to a pathway in cells that helps control how they grow, divide, and develop. YAP (Yes-associated protein) and TAZ (transcriptional co-activator with PDZ-binding motif) are proteins that move into the cell nucleus to turn on genes that promote cell growth and survival. This pathway is crucial in processes like tissue regeneration and can be involved in diseases such as cancer when it becomes dysregulated.

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      community Has anyone else seen this encouraging verteporfin case study?

      in Progress Pictures  37 upvotes 9 months ago
      The conversation discusses the potential use of verteporfin for hair loss treatment, with one user mentioning their surgeon's interest in trying it and another noting its research status and clinical use as a YAP inhibitor. Some users debate the market size, availability of generics, and the optimism in the hair loss community regarding new treatments.

      community Verteporfin and Microneedling

      in Treatments 3 months ago
      Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.